This book will equip graduate students in the mathematical sciences to understand and model the epidemiological and experimental data encountered in genetics research. It will serve both as a graduate text and a reference book.
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Kenneth Lange is the Rosenfeld Professor of Computational Genetics in the Departments of Computational Medicine, Human Genetics, and Statistics at the University of California, Los Angeles. He served as chair of the UCLA Department of Computational Medicine for 9 years and as chair of the UCLA Department of Human Genetics for 12 years. He has authored five other books, including Mathematical and Statistical Methods for Genetic Analysis (Springer, 2002), Numerical Analysis for Statisticians (Springer, 2010) and Optimization (Springer, 2013). In 2021 he was elected to the National Academy of Sciences.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the past decade, geneticists have cloned scores of Mendelian disease genes and constructed a rough draft of the entire human genome. The unprecedented insights into human disease and evolution offered by mapping, cloning, and sequencing will transform medicine and agriculture. This revolution depends vitally on the contributions of applied mathematicians, statisticians, and computer scientists. Mathematical and Statistical Methods for Genetic Analysis is written to equip students in the mathematical sciences to understand and model the epidemiological and experimental data encountered in genetics research. Mathematical, statistical, and computational principles relevant to this task are developed hand in hand with applications to population genetics, gene mapping, risk prediction, testing of epidemiological hypotheses, molecular evolution, and DNA sequence analysis. Many specialized topics are covered that are currently accessible only in journal articles. This second edition expands the original edition by over 100 pages and includes new material on DNA sequence analysis, diffusion processes, binding domain identification, Bayesian estimation of haplotype frequencies, case-control association studies, the gamete competition model, QTL mapping and factor analysis, the Lander-Green-Kruglyak algorithm of pedigree analysis, and codon and rate variation models in molecular phylogeny. Sprinkled throughout the chapters are many new problems. 388 pp. Englisch. Bestandsnummer des Verkäufers 9781468495560
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written to equip students in the mathematical siences to understand and model the epidemiological and experimental data encountered in genetics research. This second edition expands the original edition by over 100 pages and includes new material. Sprin. Bestandsnummer des Verkäufers 4205313
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book will equip graduate students in the mathematical sciences tounderstand and model the epidemiological and experimental dataencountered in genetics research. It will serve both as a graduatetext and a reference book.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 388 pp. Englisch. Bestandsnummer des Verkäufers 9781468495560
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