Discovering and Developing Molecules with Optimal Drug-Like Properties - Softcover

Softcover

ISBN 10: 1493914006 ISBN 13: 9781493914005

Verlag: Springer, 2014

Inhaltsangabe

.- 1 Developability Assessment and Risk Management During Drug Discovery

 

.- 2 Discovery Formulations - Approaches and Practices in Early Preclinical Development

 

.- 3 Enabling Discovery Through Leveraging and Miniaturizing Pharmaceutical Principles and Processes

 

.- 4 Diagnosing Biopharmaceutical Limitations

 

.- 5 The Importance of Molecular Design Principles in Delivering High Quality Pharmaceutical Candidates

 

.- 6 Predictive Approaches to Establishing, Understanding, and Communicating Risk with Emphasis on Early Development

 

.- 7 Strategies and Methods for Drug Candidate Phase Optimization in Discovery Space

.- 8 Efficient Laboratory Methods to Assess Risk and Design Formulations

 

.- 9 Advanced X-ray Analytical Methods to Understand Structure, Properties and Risk

 

.- 10 Performance and Characterization of Amorphous Solid Dispersions: An Overview

 

.- 11 Hot-Melt Extrusion: The Process-Product-Performance Interplay

 

.- 12 Practical Considerations for Spray Dried Formulation and Process Development

 

.- 13 Nanosizing: "End-to-End" Formulation Strategy for Poorly-Water- Soluble Molecules

 

.- 14 Leveraging Solid State Form and Physiochemical Properties for Early Clinical Formulation Efforts:   Opportunities and Challenges during Telcagepant Liquid Capsule Development.

Details zur Ausgabe

• Verlag: Springer
• Erscheinungsdatum: 2014
• ISBN 10: 1493914006
• ISBN 13: 9781493914005
• Einband: Paperback
• Sprache: Englisch