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Kinase Screening and Profiling: Methods and Protocols: 1360 (Methods in Molecular Biology) - Hardcover
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<P>THIS VOLUME FOCUSES ON SCREENING AND PROFILING KINASE INHIBITORS OR ACTIVATORS. CHAPTERS IN THIS BOOK COVER SEVERAL FACETS OF THE DRUG DISCOVERY PROCESSES STARTING WITH TARGET IDENTIFICATION, AND ASSAY DEVELOPMENT AND SCREENING CHEMICAL LIBRARIES FOR HIT IDENTIFICATION AND LEAD OPTIMIZATION. THE PROFILING PORTION OF <I>KINASE SCREENING AND PROFILING: METHODS AND PROTOCOLS</I> DISCUSSES SEVERAL STRATEGIES AND TECHNIQUES THAT ARE REQUIRED TO MINIMIZE OFF TARGET HITS AND REDUCE CELLULAR TOXICITIES THAT ARE CAUSED BY LIABILITY KINASES. WRITTEN IN THE HIGHLY SUCCESSFUL <I>METHODS IN MOLECULAR BIOLOGY </I>SERIES FORMAT, CHAPTERS INCLUDE INTRODUCTIONS TO THEIR RESPECTIVE TOPICS, LISTS OF THE NECESSARY MATERIALS AND REAGENTS, STEP-BY-STEP, READILY REPRODUCIBLE LABORATORY PROTOCOLS, AND TIPS ON TROUBLESHOOTING AND AVOIDING KNOWN PITFALLS.</P><P>TIMELY AND AUTHORITATIVE, <I>KINASE SCREENING AND PROFILING: METHODS AND PROTOCOLS, </I>WILL BENEFIT SCIENTISTS AND RESEARCHERS WHO ARE INTERESTED IN EXPLORING THE ROLE OF KINASES IN ACADEMIC, AS WELL AS PHARMACEUTICAL RESEARCH.</P>
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This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.
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- VerlagHumana
- Erscheinungsdatum2015
- ISBN 10 1493930729
- ISBN 13 9781493930722
- EinbandTapa dura
- Auflage1
- Anzahl der Seiten223
- HerausgeberZegzouti Hicham, Goueli Said A.
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Kinase Screening and Profiling
Verlag:
Springer New York Okt 2015
(2015)
ISBN 10: 1493930729
ISBN 13: 9781493930722
Neu
Hardcover
Anzahl: 2
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Bewertung
Buchbeschreibung Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research. 236 pp. Englisch. Bestandsnummer des Verkäufers 9781493930722
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Kinase Screening and Profiling
Verlag:
Springer New York
(2015)
ISBN 10: 1493930729
ISBN 13: 9781493930722
Neu
Hardcover
Anzahl: > 20
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Buchbeschreibung Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes cutting-edge methods and protocolsProvides step-by-step detail essential for reproducible resultsContains key notes and implementation advice from the expertsThis volume focuses on screening and profiling kinase inhibito. Bestandsnummer des Verkäufers 32581684
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Kinase Screening and Profiling : Methods and Protocols
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Buchbeschreibung Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research. Bestandsnummer des Verkäufers 9781493930722
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