Bioconjugation: Methods and Protocols (Methods in Molecular Biology, 2033, Band 2033) - Hardcover

 
9781493996537: Bioconjugation: Methods and Protocols (Methods in Molecular Biology, 2033, Band 2033)
Hardcover
ISBN 10: 1493996533 ISBN 13: 9781493996537
Verlag: Humana, 2019

Inhaltsangabe

This book explores well-established and emerging conjugation strategies that are relevant for proteins used in the field of precision medicine, focusing on techniques that are suitable for antibodies, antibody-fragments such as Fabs, scFvs, or nanobodies, scaffold proteins such as FN3 or DARPin, peptides, or model proteins. Although centered on the development of bioconjugates rather than their application, most protocols also show the conjugation of the targeting vehicle to a diagnostic or therapeutic entity, with the end-product most often being an antibody-drug conjugate, an optical probe, a nanomedicine, or a radiopharmaceutical. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 


Authoritative and practical, Bioconjugation: Methods and Protocols is an ideal guide for researchers looking toward precision medicine in order to expand the vital field of drug discovery.

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This book explores well-established and emerging conjugation strategies that are relevant for proteins used in the field of precision medicine, focusing on techniques that are suitable for antibodies, antibody-fragments such as Fabs, scFvs, or nanobodies, scaffold proteins such as FN3 or DARPin, peptides, or model proteins. Although centered on the development of bioconjugates rather than their application, most protocols also show the conjugation of the targeting vehicle to a diagnostic or therapeutic entity, with the end-product most often being an antibody-drug conjugate, an optical probe, a nanomedicine, or a radiopharmaceutical. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 


Authoritative and practical, Bioconjugation: Methods and Protocols is an ideal guide for researchers looking toward precision medicine in order to expand the vital field of drug discovery.

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Verlag
Humana
Erscheinungsdatum
2019
Sprache
Englisch
ISBN 10 
1493996533
ISBN 13 
9781493996537
Einband
Gebundene Ausgabe
Auflage
1
Anzahl der Seiten
328
Herausgeber
Massa Sam, Devoogdt Nick
Kontakt zum Hersteller
preigu GmbH & Co. KG
mail@preigu.de

Lengericher Landstr. 19
Osnabrück
Niedersachsen
49078
Deutschland

Weitere beliebte Ausgaben desselben Titels

9781493996568: Bioconjugation: Methods and Protocols (Methods in Molecular Biology, Band 2033)

Vorgestellte Ausgabe

ISBN 10:  1493996568 ISBN 13:  9781493996568
Verlag: Humana, 2020
Softcover