Autophagy and Signaling (Methods in Signal Transduction) - Hardcover

Hardcover

ISBN 10: 1498731899 ISBN 13: 9781498731898

Verlag: Taylor & Francis Inc, 2017

Inhaltsangabe

Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the status and future directions of autophagy signaling research with respect to different aspects of health and disease. These include the roles of autophagy in regulating cell fate, immune response and host defense, nutrient sensing and metabolism, neural functions and homeostasis. The mechanisms and significance of cross-talk between autophagy and other cellular processes is also explored. Lastly, alterations in autophagy observed in aging and age-related pathologies are described.

Über diesen Titel

Über die Autorin bzw. den Autor

Esther Wong graduated from the National University of Singapore with her PhD in 2004. She is an Assistant Professor with the School of Biological Sciences at Nanyang Technological University in Singapore. Her research focuses on autophagy, a cellular quality control pathway involved in protein degradation by lysosomes. The overall goal is to elucidate yet unknown mechanisms in the degradation of proteins by autophagy and how the related defects result in accumulation of damaged components, proteotoxicity and loss of cognitive functions associated with neurodegeneration and aging.

Details zur Ausgabe

• Verlag: Taylor & Francis Inc
• Erscheinungsdatum: 2017
• Sprache: Englisch
• ISBN 10: 1498731899
• ISBN 13: 9781498731898
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 267
• Herausgeber: Wong Esther
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Taylor & Francis Verlag GmbH; GPSR@taylorandfrancis.com; ; Kaufingerstraße 24, 80331 München, Germany; München; Deutschland