This volume examines the various aspects of post-transcriptional RNA processing, including biosynthetic, genetic, and functional aspects of nucleoside modification and editing by nucleoside conversion as well as by nucleoside insertion/deletion.Written by leading researchers in the field, it includes descriptions of the different types of modification/editing, identification of the correspondending enzymes, discussion of cis- and trans- acting sequences, machineries, mechanisms, cellular locations, the biological role of individual modified/edited bases, involvement in diseases like cancer and AIDS, and possible evolutionaly connections between different processes.Modification and Editing of RNA is a valuable reference for researchers, teachers and students, and will be a useful tool for the planning of future research to solve many questions that remain.
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This volume examines the various aspects of post–transcriptional RNA processing, including biosynthetic, genetic, and functional aspects of nucleotide modification and editing by nucleotide conversion as well as by nucleotide insertion/deletion. It covers techniques for identification and localization of modified nucleosides in RNA and chemical synthesis of RNA with site specific incorporation of natural and/or synthetic modified nucleosides.
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