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Functional Disorders of the Gastrointestinal Tract (Solvay Pharmaceutical Conferences) - Hardcover

 
9781586034863: Functional Disorders of the Gastrointestinal Tract (Solvay Pharmaceutical Conferences)
Hardcover
ISBN 10: 1586034863 ISBN 13: 9781586034863
Verlag: IOS Press, 2005

Inhaltsangabe

Significant progress has been made in several areas of gastroenterology over the last two decades. The understanding of physiology of gastrointestinal tract covering motility, sensitivity, absorption, and molecular biology of gastrointestinal cancers, particularly colorectal cancer, has immensely improved. Recent years were dominated by increased public attention focused on functional bowel disorders. Irritable bowel syndrome is a functional bowel disorder characterized by abdominal pain and discomfort without clearly demonstrable organic cause leading to altered bowel habits. Since the prevalence of irritable bowel syndrome is high, it represents a significant societal and economic burden. Better understanding of the function of the enteric nervous system supported by the evidence that pain and discomfort experienced by the patients is due to hypersensitivity of vagal and spinal sensory neurons allowed for selective targeting receptors expressed by the afferent neurons for therapeutic intervention. Emerging therapies for irritable bowel syndrome, such as tegaserod, alosetron and cilansetron, affect serotonergic system. This publication may be of interest to experts from a variety of disciplines including medicine, physiology and pathophysiology, medicinal chemistry, pharmacology, and molecular genetics as well as to the general public.

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Von der hinteren Coverseite

Significant progress has been made in several areas of gastroenterology over the last two decades. The understanding of physiology of gastrointestinal tract covering motility, sensitivity, absorption, and molecular biology of gastrointestinal cancers, particularly colorectal cancer, has immensely improved. Recent years were dominated by increased public attention focused on functional bowel disorders. Irritable bowel syndrome is a functional bowel disorder characterized by abdominal pain and discomfort without clearly demonstrable organic cause leading to altered bowel habits. Since the prevalence of irritable bowel syndrome is high, it represents a significant societal and economic burden. Better understanding of the function of the enteric nervous system supported by the evidence that pain and discomfort experienced by the patients is due to hypersensitivity of vagal and spinal sensory neurons allowed for selective targeting receptors expressed by the afferent neurons for therapeutic intervention. Emerging therapies for irritable bowel syndrome, such as tegaserod, alosetron and cilansetron, affect the serotonergic system. This publication is of interest to experts from a variety of disciplines including medicine, physiology and pathophysiology, medicinal chemistry, pharmacology, and molecular genetics as well as to the general public.

Aus dem Klappentext

Significant progress has been made in several areas of gastroenterology over the last two decades. The understanding of physiology of gastrointestinal tract covering motility, sensitivity, absorption, and molecular biology of gastrointestinal cancers, particularly colorectal cancer, has immensely improved. Recent years were dominated by increased public attention focused on functional bowel disorders. Irritable bowel syndrome is a functional bowel disorder characterized by abdominal pain and discomfort without clearly demonstrable organic cause leading to altered bowel habits. Since the prevalence of irritable bowel syndrome is high, it represents a significant societal and economic burden. Better understanding of the function of the enteric nervous system supported by the evidence that pain and discomfort experienced by the patients is due to hypersensitivity of vagal and spinal sensory neurons allowed for selective targeting receptors expressed by the afferent neurons for therapeutic intervention. Emerging therapies for irritable bowel syndrome, such as tegaserod, alosetron and cilansetron, affect the serotonergic system. This publication is of interest to experts from a variety of disciplines including medicine, physiology and pathophysiology, medicinal chemistry, pharmacology, and molecular genetics as well as to the general public.

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Verlag
IOS Press
Erscheinungsdatum
2005
Sprache
Englisch
ISBN 10 
1586034863
ISBN 13 
9781586034863
Einband
Gebundene Ausgabe
Anzahl der Seiten
144
Herausgeber
Malagelada J. R., Preuschoff U.
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Buchpark GmbH
gpsr@buchpark.de

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Deutschland