Receptor Signal Transduction Protocols - Hardcover

Hardcover

ISBN 10: 1588293297 ISBN 13: 9781588293299

Verlag: Humana Press, 2004

Inhaltsangabe

This new edition combines updates of key chapters from the first edition with a large number of new key methodologies that have emerged more recently for studying G protein-coupled receptors (GPCRs) and events immediately downstream of their activation. The methods are focused primarily on events at the receptor level, including ligand binding, the genetic manipulation of receptors, the generation of model cell lines in which to study them, and the interaction and activation of G-proteins. Additional methods concentrate on receptor expression and localization, receptor internalization and post-translational modification, GPCR-protein interactions, and the use of knock-out and knock-in strategies for determining the physiological roles of receptors.

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Críticas

From reviews of the first edition... "...should be present in all cellular and molecular laboratories of the world." -Cellular and Molecular Biology "...enthusiastically recommend[ed]...should figure prominently in any laboratory involved in receptor biochemistry, molecular biology, and pharmacology." -Trends in Pharmacological Sciences

Details zur Ausgabe

• Verlag: Humana Press
• Erscheinungsdatum: 2004
• Sprache: Englisch
• ISBN 10: 1588293297
• ISBN 13: 9781588293299
• Einband: Tapa dura
• Auflage: 2
• Anzahl der Seiten: 418
• Herausgeber: Willars Gary B., Challiss R. A. John
• Kontakt zum Hersteller: Nicht verfügbar