Measuring Cell Mechanics (Colloquium Series on Quantitative Cell Biology) - Softcover

Gardel, Margaret; Oakes, Patrick

Softcover

ISBN 10: 1615046984 ISBN 13: 9781615046980

Verlag: Biota Publishing, 2015

Inhaltsangabe

Páginas:76Géneros:12:PSD:MolecularbiologySinopsis:Cellsareinherentlyphysicalentitiesthatbothexperiencemechanicalforcesfromtheirexternalenvironmentandgeneratetheirowninternalforcestodrivecellmotion.Ourparticularaimhereistopresentthereaderwithanintroductiontotheprimarytoolsusedtomeasurethesemechanicalinteractionsandthematerialpropertiesofcellsthatresultfromthem.Theseapproachescanbeappliedtoadiversearrayofphysiologicalprocessesandsystems,providingimportantinsightintotheregulatoryrolesofmechanicalinteractionsincells.Wecovertechniquesatboththemolecularandcellularscales,includingthosethatactivelyandpassivelyprobethesystem.Alongthewaywecoverthefundamentalprinciplesofeachapproach,whileemphasizingtherelevantlengthandtimescales,alongwiththetypicalmagnitudesofthemeasurementsthatcanbemade.Eachsectionendsbyhighlightingusesofthevarioustechniquesinrecentrelevantpublications,illustratingtheexcitingfutureofcellmechanicsinquantitativecellbiologyresearch._,

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Reseña del editor:

Cells are inherently physical entities that both experience mechanical forces from their external environment and generate their own internal forces to drive cell motion. Our particular aim here is to present the reader with an introduction to the primary tools used to measure these mechanical interactions and the material properties of cells that result from them. These approaches can be applied to a diverse array of physiological processes and systems, providing important insight into the regulatory roles of mechanical interactions in cells. We cover techniques at both the molecular and cellular scales, including those that actively and passively probe the system. Along the way we cover the fundamental principles of each approach, while emphasizing the relevant length and timescales, along with the typical magnitudes of the measurements that can be made. Each section ends by highlighting uses of the various techniques in recent relevant publications, illustrating the exciting future of cell mechanics in quantitative cell biology research.

Biografía del autor:

University of Chicago University of Chicago

Über diese Auflage

• Verlag: Biota Publishing
• Erscheinungsdatum: 2015
• ISBN 10: 1615046984
• ISBN 13: 9781615046980
• Einband: Tapa blanda
• Anzahl der Seiten: 76