Pathophysiology of Pulmonary Hypertension (Colloquium Series on Integrated Systems Physiology: from Molecule to Function to Disease) - Softcover

Gao, Yuansheng; Raj, J. Usha

Softcover

ISBN 10: 1615047603 ISBN 13: 9781615047604

Verlag: Morgan & Claypool Life Sciences, 2017

Inhaltsangabe

Pulmonary hypertension is a life-threatening disease with no known cure. Here we provide a concise yet comprehensive review of the current knowledge about the pathophysiology of pulmonary hypertension (PH). The underlying signaling mechanisms involved in pulmonary vascular remodeling and the exaggerated vascular contractility, two characteristic features of pulmonary hypertension, are discussed in depth. The roles of inflammation, immunity, and right ventricular function in the pathobiology of pulmonary hypertension are discussed. The epidemiology of the five groups of pulmonary hypertension (World Health Organization classification; Nice, 2013) is also briefly described. A clear understanding of our current knowledge about the pathogenesis of PH is essential for further exploration of the underlying mechanisms involved in this disease and for the development of new therapeutic modalities. This book should be of interest to researchers and graduate students, both in basic research and in clinical settings, in the fields of pulmonary vascular biology and pulmonary hypertension.

Über diesen Titel

Über die Autorin bzw. den Autor

Yuansheng Gao, Ph.D., received his Ph.D. in Physiology (1990; advisor: Paul M. Vanhoutte) from Mayo Graduate School, Rochester, Minnesota and postdoctoral training in Professor Vanhoutte's laboratory at the Baylor College of Medicine, Houston, Texas (1990-1992). He worked in Professor J. Usha Raj's laboratory from 1992 to 2002 as an Adjunct Assistant/Associate Professor at Harbor-UCLA Medical Center, Los Angeles, California. Since 2002 he serves as Professor of Pathophysiology in Peking University Health Science Center, Beijing, China. He has been an Honorary Professor of Department of Pharmacology and Pharmacy in the University of Hong Kong, China since 2014. He has served as the council member of Asian Society for Vascular Biology since 2005 and the review editor for the journal Frontiers in Vascular Physiology since 2011. He has worked on the signaling transduction of pulmonary and coronary vasculature for nearly 30 years and has published over 90 original research and review articles in this field.

Details zur Ausgabe

• Verlag: Morgan & Claypool Life Sciences
• Erscheinungsdatum: 2017
• Sprache: Englisch
• ISBN 10: 1615047603
• ISBN 13: 9781615047604
• Einband: Taschenbuch
• Anzahl der Seiten: 120
• Herausgeber: Granger D. Neil
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: preigu; mail@preigu.de; ; Lengericher Landstr. 19; Osnabrück; 49078; Deutschland