Colorectal Cancer: Evidence-based Chemotherapy Strategies (Current Clinical Oncology) - Softcover

Softcover

ISBN 10: 1617377562 ISBN 13: 9781617377563

Verlag: Humana, 2010

Inhaltsangabe

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Reseña del editor

Management options for patients with colorectal cancer have undergone d- matic changes over the past decade. Whereas at the start of 1996 only one drug, 5-Fluorouracil, was available for the treatment of this disease, a mere 10 yr later, six drugs are licensed for use in colorectal cancer, and others are in the late phases of clinical development. Likewise, surgical and ablative options, as well as an array of supportive medications, have shown substantial progress and undergone a dramatic proliferation over the past decade. With the increased number of therapeutic options from which to choose, the clinician is better able to offer effective therapy to the patient with colorectal cancer. The clinician is challenged, however, to keep up with the rapidly changing landscape and the rapidly emerging data that shape the options for treatment today and tom- row. In this text, leaders in the management of colorectal cancer review the current literature that has led us to where we are today. Critical evaluations of the data are offered, and evidence-based recommendations are made.

Reseña del editor

Recent advances in the understanding of the biology of colorectal cancer have radically transformed the treatment options available to clinicians, leaving textbooks written only two years ago completely out of date. This evidence-based and data-driven guide presents reviews of cutting-edge therapies for colorectal cancer, all articulated by leading experts in the field. This integrated and focused consideration of colorectal management includes reviews of cytotoxic chemotherapy, targeted biologic therapies, as well as updates on adjuvant chemotherapy for colon cancer and combined modality management of rectal cancers. Attention is also focussed on the role of potentially curative multi-modality management of liver metastases, with considerations of the role of liver resection and discussions of non-surgical ablative therapies. Supportive issues are also considered, including contributions from experts in pain management and oncology nursing. The reviews presented here are concise, up-to-date, and are organized with the treating practitioner in mind. Opening chapters outline contemporary thinking on the biology of colorectal cancer, and methods of possible prevention utilizing chemoprevention and screening. Subsequent chapters present cutting-edge uses of cytotoxic chemotherapy and review the potential for incorporating innovative biological therapy. Ample consideration is given to practical issues related to colorectal chemotherapy, specifically radiological evaluation of colorectal cancer treatment and supporting patients through chemotherapy, including pain management. The concluding chapter is devoted to the exploration of and implications of emerging new drug paradigms and their potential impact on colorectal cancer treatment. This unique text offers the practitioner a concise, authoritative reference, so that recent advancements and understanding may be digested, disseminated, and rapidly applied to the treatment of the colorectal cancer patient.

Details zur Ausgabe

• Verlag: Humana
• Erscheinungsdatum: 2010
• ISBN 10: 1617377562
• ISBN 13: 9781617377563
• Einband: Tapa blanda
• Sprache: Englisch
• Anzahl der Seiten: 304
• Herausgeber: Saltz Leonard B.