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Breast Cancer: From Fundamental Biology to Therapeutic Strategies (Cold Spring Harbor Perspectives in Medicine) - Hardcover

 
9781621824664: Breast Cancer: From Fundamental Biology to Therapeutic Strategies (Cold Spring Harbor Perspectives in Medicine)
Hardcover
ISBN 10: 1621824667 ISBN 13: 9781621824664
Verlag: Cold Spring Harbor Laboratory Press,U.S., 2024

Inhaltsangabe

Breast cancer is diagnosed in over two million people each year and kills more than six hundred thousand. It has numerous histological subtypes, each with different molecular properties, and a variety of genetic and environmental factors increase an individual's risk of developing the disease.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews our understanding of breast cancer epidemiology, the molecular and cellular mechanisms underlying its progression, and recent advances in tumor prevention, detection and treatment. The contributors discuss how work using animal models, patient-derived xenografts, and organoid cultures, together with new imaging approaches, is providing new insights into the molecular pathology of breast cancer. In addition, they examine genetic and genomic determinants, the role of chromatin, and research into intra- and inter-tumor heterogeneity.

The authors also discuss tumor dormancy, the importance of the immune system in breast cancer, and ways this may be harnessed in tumor immunotherapy. This volume is therefore a vital reference for all biologists seeking to understand the biological basis of cancer, as well as immunologists and oncologists dedicated to combating this deadly disease.

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Über die Autorinnen und Autoren

Jane Visvader is Division Head of the Cancer Biology and Stem, Walter and Eliza Hall Institute of Medical Research (WEHI), Australia

Jeffrey M Rosen is Professor of Molecular & Cell and Leader of the Breast Cancer Program at the Dan L Duncan Comprehensive Cancer Center at the Baylor College of Medicine

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Verlag
Cold Spring Harbor Laboratory Press,U.S.
Erscheinungsdatum
2024
Sprache
Englisch
ISBN 10 
1621824667
ISBN 13 
9781621824664
Einband
Gebundene Ausgabe
Anzahl der Seiten
360
Herausgeber
Visvader Jane E., Rosen Jeffrey M., Aparicio Samuel
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Verantwortliche Person
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