Prevention is the Cure!: A Scientist's Guide to Extending Your Life - Softcover

Sancilio Ph.D., Frederick D.

Softcover

ISBN 10: 1630474258 ISBN 13: 9781630474256

Verlag: Morgan James Publishing, 2015

Inhaltsangabe

An amazing discussion from a scientist on the nature of health, sickness, and what we all can do to remain vibrant as we grow older, Prevention is the Cure! will take you through the root causes of most diseases and guide you in ways that can save your life and the lives of others. Discover the four primary causes of illnesses and how to avoid them. Learn the ten commandments of longevity, the secret habits of centenarians, and, most important, learn how you can remain youthful well into your eighties and nineties! As a successful scientist, businessman, and community leader, Dr. Fred Sancilio shares his thoughts on the tragic demise of his own father, the tipping point to his quest to find the truth about why some people always seem to be sick, while others are perpetually healthy. Learn how scientists study the differences between eating habits of various populations and the connection between the incredible health of the Intuits of Greenland and a diet that could well benefit mankind forever. Prevention is the Cure! will become your guidebook to a long and healthy life. It will lay the groundwork for a robust and active future.

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Über die Autorin bzw. den Autor

Dr. Fred Sancilio has published more than twenty articles in peer-reviewed scientific journals, holds fourteen domestic and international patents, and contributed to the development of more than one thousand drugs marketed in the United States, Europe, and Asia. The founder of aaiPharma, a major contract pharmaceutical research company, and Sancilio & Company, a rapidly growing biopharmaceutical company based in Florida, Sancilio’s Prevention is the Cure! is his Xth book.

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Prevention is the Cure!

A Scientist's Guide to Extending Your Life

By Frederick D. Sancilio

Morgan James Publishing

Copyright © 2015 Dr. Frederick D. Sancilio, Ph.D.
All rights reserved.

ISBN: 978-1-63047-425-6

Contents

Foreword By Jonny Bowden, PhD, CNS, 
Introduction An Ounce of Prevention, 
Chapter 1 In the Beginning, 
Chapter 2 Conquering Heart Disease, 
Chapter 3 The Lifelong Brain, 
Chapter 4 Let's Raise Smarter, Healthier Children, 
Chapter 5 Can We Prevent Cancer?, 
Chapter 6 The End of Type 2 Diabetes, 
Chapter 7 Reversing the Trends, 
Acknowledgments, 
Appendix Omega-3 Recommended Daily Dosages, 
Bibliography, 
About the Author, 

CHAPTER 1

IN THE BEGINNING

So God created the great creatures of the sea and every living thing with which the water teems and that moves about in it ... and God saw that it was good.

— Genesis 1:21

Who would have thought that an editorial in an obscure Danish medical newspaper — unsigned and anonymous, no less — would start a revolution?

Yet that's exactly what happened.

The anonymous author began by pointing to studies showing that the native Inuit people of Greenland (then referred to as "Eskimos") had an exceedingly low incidence of death from myocardial infarction (heart attack). That alone would not have been surprising except for one inconvenient fact.

The Inuit ate a ton of fat.

And this did not fit well with conventional wisdom of the time.

It was 1968, and the low-fat forces were just gearing up for a battle that would ultimately divide the nutrition community into two factions, and make the partisanship of the US congress in the early twenty-first century look like a Disney movie. High-fat diets were not supposed to be healthy, let alone prevent heart disease. Yet the Inuit consumed a ton of fatty fish and fatty seal, and had vanishingly low levels of heart disease.

So our anonymous author issued a warning to the Danish medical community.

The warning was, "Time is running out." Western influences were changing the lifestyle and diet of the Inuits. Unless Danish researchers soon studied this issue, the opportunity to discover why Inuits had so little heart disease would be lost — and perhaps new insights into how to prevent heart attacks.

Why Danish researchers? Because Greenland — the scene of the paradox — was a colony of Denmark. (It's independent today, but still part of the "Kingdom of Denmark.") The startling fact was that 40 percent of deaths of males aged forty-five to sixty-five years living in Denmark resulted from heart attacks, while in Greenland, it was only 5.3 percent!

It was the responsibility, said the editorial — indeed it was the duty — of Danish scientists to take command of this endeavor.

Conventional wisdom at the time insisted that consuming a diet high in animal fat was the primary cause of cardiovascular disease. Many studies, including the famous Framingham Heart Study, which began in 1948 (and continues today), indicated at first that high-fat diets increased the risk of heart disease. Diets high in saturated animal fat, from bacon to butter to red meat, seemed to increase the odds, reducing not just the length but also the quality of life. Among other flaws, the Framingham researchers had no clue about the diversity of fats. While today we know some dietary fats are implicated in heart disease (trans fats), others are benign (monounsaturated fats), and some actually protect the heart — they reduce the risk of cardiovascular disease by suppressing inflammation, lowering triglycerides, and rendering cell membranes more fluid.

Fixated on the challenge of studying the epidemiological anomaly of Greenland's natives, a Danish physician, Hans Olaf Bang, told his young protégé, Jørn Dyerberg, "We simply have to go there and solve this riddle." As fate would have it, their opportunity to do just that came soon after.

And it happened when an outbreak of chicken pox threatened to decimate the Inuit population.

The Danish government asked for volunteer doctors to go to Greenland with medical supplies to fight the epidemic. Deciding to take advantage of the opportunity, Bang and Dyerberg not only volunteered, they also cobbled together $6,000 for the supplies they would need to collect and store 130 Inuit blood samples. Their plan was to bring these samples back to Denmark, and test them in the lab in the hopes of getting to the bottom of the mystery of why so few Inuits dropped dead from heart attacks.

The government asked the two doctors to set up a medical station in the village Igdlorssuit (translation, "The Big House"), located on an island off Greenland's western coastline. The problem was, the only way to get to Igdlorssuit was by dogsledding over one hundred miles of sea ice. Naively thinking they could ride in the sleds, Bang and Dyerberg hired experienced Inuits as drivers. But their equipment was much too heavy, so they had to run alongside the dogs. "This was not easy," Dyerberg recalls, "as we were in a dress that does not invite running."

Three days of dogsledding and two nights of sleeping outdoors in the cold tundra later, they found themselves living and working in very meager quarters — a building fashioned from piles of stones. There was no concrete to plug the cracks that let in cold drafts. But they were lucky; the temperatures at that time of year ranged from minus 4 to plus 10 degrees Fahrenheit. It was summer!

Weeks later, and back home in Denmark, Bang and Dyerberg were surprised to discover even though Inuits tended to be obese, their blood cholesterols were still lower than those of most Europeans, but not enough to explain the low rate of heart attacks. They published these results in The Lancet (1971). Next, using an old gas chromatograph, the two doctors began the tedious task of analyzing all the compounds in each Inuit blood sample. This process took two years, during which they found two compounds they had never heard of before, which they called "mystery X" and "mystery Y." At first, Bang and Dyerberg weren't sure, but they believed these compounds to be fats specifically from fish — compounds now called EPA and DHA.

About this time, Dyerberg recalls, "some new research came out indicating omega-6 fatty acids (AA and LA) cause blood to clot, so we suddenly got the idea that our fatty acids do the opposite." While in Igdlorssuit, they had observed that when an Inuit got a nosebleed (a frequent occurrence in extremely cold, dry air), the bleeding seemed to take longer to stop than what they remembered occurring back home. But this was only a casual observation. Measurements needed to be taken to find out how true it was. So, the two found themselves going back to Igdlorssuit. This time Bang and Dyerberg made tiny cuts on the arms of the same Inuits who earlier had provided them blood samples and timed how long it took for the bleeding to stop. The finding was it took an average of eight minutes, twice as long as it took when they performed the same experiment on fellow Danes. The only explanation was that omega-3 fatty acids decreased the speed of the clotting process.

The second discovery led Bang and Dyerberg to publish another paper in 1975 that appeared in the American Journal of Clinical Nutrition. For the first time they mentioned EPA and DHA and commented on the difference between the levels of these...

Details zur Ausgabe

• Verlag: Morgan James Publishing
• Erscheinungsdatum: 2015
• Sprache: Englisch
• ISBN 10: 1630474258
• ISBN 13: 9781630474256
• Einband: Taschenbuch
• Auflage: 1
• Anzahl der Seiten: 270
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: preigu; mail@preigu.de; ; Lengericher Landstr. 19; Osnabrück; 49078; Deutschland