Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles: Application to Drug Delivery System (Iop Concise Physics) - Hardcover

Ye, Huilin; Shen, Zhiqiang; Li, Ying

 
9781643277936: Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles: Application to Drug Delivery System (Iop Concise Physics)
Hardcover
ISBN 10: 1643277936 ISBN 13: 9781643277936
Verlag: IOP Concise Physics, 2020

Inhaltsangabe

Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.

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Über die Autorin bzw. den Autor

Huilin Ye is a PhD candidate in Mechanical Engineering at University of Connecticut. His research interest is mainly of developing high-fidelity computational methods in biosystem, especially for the blood flow. The novel numerical scheme has been successfully applied in the targeted drug delivery system for capturing the dynamic motion of micro- and nano-particles in blood flow. Ye's works have been recognized by fellowships and awards including Generic Electric Fellowship for Innovation and Best paper award of FDTC Student paper competition in EMI(2018) from ASCE.

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Verlag
IOP Concise Physics
Erscheinungsdatum
2020
Sprache
Englisch
ISBN 10 
1643277936
ISBN 13 
9781643277936
Einband
Gebundene Ausgabe
Anzahl der Seiten
114
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
preigu
mail@preigu.de

Lengericher Landstr. 19
Osnabrück
49078
Deutschland

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Vorgestellte Ausgabe

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Verlag: IOP Concise Physics, 2020
Softcover