Ubiquitin: Proteasome Pathway (Biochemistry, 18) - Hardcover

 
9781838804329: Ubiquitin: Proteasome Pathway (Biochemistry, 18)
Hardcover
ISBN 10: 1838804323 ISBN 13: 9781838804329
Verlag: IntechOpen, 2020

Inhaltsangabe

The ubiquitin-proteasome pathway consists of ubiquitin, substrate proteins, E1 enzymes, E2 enzymes, E3 enzymes, and proteasome, which acts in a series of enzymatic reaction chains to ubiquitinate substrate proteins such as surplus and misfolded proteins for degradation by the proteasome to maintain the balance between protein synthesis and degradation in a cell and tissue. Moreover, deubiquitinating enzymes can remove the attached ubiquitin chain, which results in a reverse ubiquitination-deubiquitination process involved in multiple biological processes in a cell and tissue. The changes of components in the ubiquitin-proteasome pathway are associated with multiple pathophysiological processes, such as cancers and neurodegenerative diseases. This book presents the new advances in concepts, analytical methodology, and application of ubiquitin-proteasome pathway for clarification of molecular mechanisms and discovery of new therapeutic targets and drugs in different diseases.

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Verlag
IntechOpen
Erscheinungsdatum
2020
Sprache
Englisch
ISBN 10 
1838804323
ISBN 13 
9781838804329
Einband
Gebundene Ausgabe
Anzahl der Seiten
124
Herausgeber
Zhan Xianquan, Blumenberg Miroslav
Kontakt zum Hersteller
preigu GmbH & Co. KG
mail@preigu.de

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