The Organic Chemistry of Isotopic Labelling: Rsc - Hardcover

Hanson, James R.

 
9781849731881: The Organic Chemistry of Isotopic Labelling: Rsc
Hardcover
ISBN 10: 1849731888 ISBN 13: 9781849731881
Verlag: ROYAL SOCIETY OF CHEMISTRY, 2011

Inhaltsangabe

The chemical synthesis of isotopically labelled compounds is a pre-requisite for many chemical, biochemical and medicinal investigations. The constraints imposed by the requirements for regiospecific labelling and, in some instances, the time-scale of the synthesis often lead to quite different synthetic strategies to those that are used for the unlabelled material. Whilst there are many specialist papers, reviews and long books devoted to particular isotopes, there is no currently available short introductory book devoted to the organic chemistry of isotopic labelling. The aim of this book is to introduce research workers to a variety of methods that have been used to achieve these synthetic labelling objectives before exploring a particular method in detail. It covers a number of different isotopes and the methods that have been used to introduce them into organic compounds. Labelling methods also provide useful undergraduate teaching examples of modern synthetic reactions and their stereochemical consequences using relatively simple substrates. The book will therefore have a wider appeal than just those involved in using isotopes in research such as environmental and pharmaceutical chemists as well as organic chemists.

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Über die Autorin bzw. den Autor

Dr JR Hanson is in the Department of Chemistry at the University of Sussex, Brighton, UK. Isotopically labelled (2H, 3H, 13C, 14C, 18O) compounds have played an important role in his research on natural product biosynthesis and terpenoid and steroid chemistry since 1959 and has involved both the preparation and detection of labelled compounds. His teaching to chemistry, biochemistry and medicinal chemistry students at the University of Sussex has included many examples of the preparation and detection of labelled compounds. He has also given lectures on this topic at various meetings.

Von der hinteren Coverseite

The chemical synthesis of isotopically labelled compounds is a pre-requisite for many chemical, biochemical and medicinal investigations. The constraints imposed by the requirements for regiospecific labelling and, in some instances, the time-scale of the synthesis often lead to quite different synthetic strategies to those that are used for the unlabelled material. Whilst there are many specialist papers, reviews and long books devoted to particular isotopes, there is no currently available short introductory book devoted to the organic chemistry of isotopic labelling. The aim of this book is to introduce research workers to a variety of methods that have been used to achieve these synthetic labelling objectives before exploring a particular method in detail. It covers a number of different isotopes and the methods that have been used to introduce them into organic compounds. Labelling methods also provide useful undergraduate teaching examples of modern synthetic reactions and their stereochemical consequences using relatively simple substrates. The book will therefore have a wider appeal than just those involved in using isotopes in research such as environmental and pharmaceutical chemists as well as organic chemists.

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Verlag
ROYAL SOCIETY OF CHEMISTRY
Erscheinungsdatum
2011
Sprache
Englisch
ISBN 10 
1849731888
ISBN 13 
9781849731881
Einband
Gebundene Ausgabe
Auflage
1
Anzahl der Seiten
184
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
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