Microbial Efflux Pumps: Current Research - Hardcover

Hardcover

ISBN 10: 1908230215 ISBN 13: 9781908230218

Verlag: Caister Academic Press Limited, 2013

Inhaltsangabe

Infectious diseases caused by bacteria remain a leading cause of death worldwide. Many of the antibiotics developed to combat bacterial infections have been rendered almost impotent due to the rapid evolution and spread of antibiotic resistance. A common and major resistance mechanism, the efflux system, enables bacteria to extrude structurally diverse antimicrobials, facilitating survival in toxic environments. The pumps also have important physiological functions, play major roles in bacterial pathogenesis and are distributed widely across diverse bacterial species. In addition a single species may harbour several different types of efflux systems: of these, active efflux has proven to be one of the most successful detoxification mechanisms used by both Gram-positive and -negative pathogens. Unravelling the intricacies of the microbial efflux systems is essential for the development of new strategies to overcome antimicrobial resistance. This has inspired a plethora of multidisciplinary research projects that have focused on the biochemistry, bioinformatics, structural and molecular biology of this fascinating field. With contributions from leading researchers in the field, this book reviews the most important current research and summarizes the most spectacular discoveries. Essential reading for all scientists with an interest in drug and antibiotic resistance in a range of different microorganisms.

Details zur Ausgabe

• Verlag: Caister Academic Press Limited
• Erscheinungsdatum: 2013
• Sprache: Englisch
• ISBN 10: 1908230215
• ISBN 13: 9781908230218
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 268
• Herausgeber: Yu Edward W, Zhang Qijing, Brown Melissa H
• Kontakt zum Hersteller: preigu GmbH & Co. KG; mail@preigu.de; ; Lengericher Landstr. 19; Osnabrück; Niedersachsen; 49078; Deutschland