With the ability to undergo both mitosis and meiosis, germ cells give rise to gametes and serve as the link between generations in sexually reproducing organisms. This collection reviews the biology of germ cells in metazoans, describing the undifferentiated state of germline stem cells, the triggers for meiotic entry, and the transcriptional and posttranscriptional controls that lead to the formation of mature gametes during spermatogenesis and oogenesis.
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Hardcover. Zustand: new. Hardcover. In sexually reproducing organisms, germ cells give rise to gametes and serve as the link between generations. A key event during germ cell development is the decision to leave mitosis and enter meiosis, leading to the formation of mature eggs and sperm. Germ cell development involves uniquegene expression programs and the establishment of epigenetic marks that ensure success during fertilization and embryo development.Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews the biology of germ cells in metazoans. The contributors describe the undifferentiated state of germline stem cells, the triggers for meiotic entry, and the transcriptional and posttranscriptional controls during spermatogenesis and oogenesis that lead to the formation of mature gametes. The expression of sex linked genes and the establishment of genomic imprinting in the germline are also covered. This volume, which includes discussions of gamete recognition proteins, eggactivation, and genetic reprogramming following nuclear transfer, is an indispensable reference for cell, molecular, and developmental biologists and anyone wishing to understand the implications of germ cell biology for reproductive technologies. With the ability to undergo both mitosis and meiosis, germ cells give rise to gametes and serve as the link between generations in sexually reproducing organisms. This collection reviews the biology of germ cells in metazoans, describing the undifferentiated state of germline stem cells, and more. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Bestandsnummer des Verkäufers 9781936113514
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