Normal Cytology: An Illustrated, Practical Guide - Hardcover

Hardcover

ISBN 10: 3031203356 ISBN 13: 9783031203350

Verlag: Springer, 2023

Inhaltsangabe

In the practice of cytopathology, cytologists frequently encounter a spectrum of benign, normal cells in samples. In fact, these normal cells frequently comprise the greatest proportion of material present on a cytology slide. This is frequently the case in Pap smears of the uterine cervix , urine samples, and lung samples such as bronchial brushings. Normal cytology can often mimic pathology leading to misdiagnoses, especially in cases with reactive and metaplastic changes. Moreover, cytopathology findings of certain neoplasms can also mimic normal cytology.

Today, cytology laboratories are no longer confined to dealing with just exfoliative specimens and superficial aspirations. With interventional radiology as well as endobronchial and endoscopic ultrasound-guided fine needle aspirations (FNA), we increasingly encounter visceral samples. Hence, cytologists are even likely to encounter normal elements from deep-seated organs. Sometimes, unexpected normalelements may be found within cytology specimens because a FNA procedure has contamination or inadvertently sampled a nearby organ or normal anatomical structure. A typical example is the finding of ganglion cells when a FNA is performed targeting a celiac node for cancer staging (Elgarby EA et al. Frequency and characterization of celiac ganglia diagnosed on fine-needle aspiration. Cytojournal. 2015; 12:4). 

Despite the importance of knowing the spectrum of normal cytology, there are limited reference materials available on this topic for cytologists. Most cytopathology texts deal with abnormal cytology. Often, the chapters in these books only devote a few sentences about normal cytology (euplasia). Our proposed book intends to fulfil this need. The book will contain a mixture of text and images (atlas). Important aspects related to cytology practice will be highlighted such as clinical relevance, differential diagnoses, mimics and pitfalls. The images will include a variety of cytology specimen preparations (e.g. direct smears, liquid based samples, touch preparations, cell blocks) and stains (e.g. Diff Quik/MGG, Papanicolaou, H&E). In selected cases, the expected immunoprofile of normal cells will be addressed. Each chapter will also include a modest list of helpful and contemporary references.

Über diesen Titel

Über die Autorin bzw. den Autor

 

Madelyn Lew, MD

Michigan Medicine Department of Pathology

2800 Plymouth Rd, Bldg 35

Ann Arbor, MI 48109

Tel: (734)936-6622

Judy C.  Pang, MD

Michigan Medicine Department of Pathology

2800 Plymouth Rd, Bldg 35

Ann Arbor, MI 48109

Tel: 734-232-0251

Liron Pantanowitz, MD PhD MHA

Michigan Medicine Department of Pathology

2800 Plymouth Rd, Bldg 35

Ann Arbor, MI 48109

Tel: 413-237-4397

Von der hinteren Coverseite

In the practice of cytopathology, cytologists frequently encounter a spectrum of benign, normal cells in samples. In fact, these normal cells frequently comprise the greatest proportion of material present on a cytology slide. This is frequently the case in Pap smears of the uterine cervix , urine samples, and lung samples such as bronchial brushings. Normal cytology can often mimic pathology leading to misdiagnoses, especially in cases with reactive and metaplastic changes. Moreover, cytopathology findings of certain neoplasms can also mimic normal cytology.

Today, cytology laboratories are no longer confined to dealing with just exfoliative specimens and superficial aspirations. With interventional radiology as well as endobronchial and endoscopic ultrasound-guided fine needle aspirations (FNA), we increasingly encounter visceral samples. Hence, cytologists are even likely to encounter normal elements from deep-seated organs. Sometimes, unexpected normal elements may be found within cytology specimens because a FNA procedure has contamination or inadvertently sampled a nearby organ or normal anatomical structure.

Despite the importance of knowing the spectrum of normal cytology, there are limited reference materials available on this topic for cytologists. Most cytopathology texts deal with abnormal cytology. Often, the chapters in these books only devote a few sentences about normal cytology (euplasia). This book intends to fulfil this need. The book contains a mixture of text and images. Important aspects related to cytology practice are highlighted such as clinical relevance, differential diagnoses, mimics and pitfalls. The images include a variety of cytology specimen preparations (e.g. direct smears, liquid based samples, touch preparations, cell blocks) and stains (e.g. Diff Quik/MGG, Papanicolaou, H&E). In selected cases, the expected immunoprofile of normal cells is addressed. Each chapter includes a modest listof helpful and contemporary references.

Details zur Ausgabe

• Verlag: Springer
• Erscheinungsdatum: 2023
• Sprache: Englisch
• ISBN 10: 3031203356
• ISBN 13: 9783031203350
• Einband: Gebundene Ausgabe
• Auflage: 1
• Anzahl der Seiten: 187
• Herausgeber: Lew Madelyn, Pang Judy, Pantanowitz Liron
• Kontakt zum Hersteller: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Deutschland