An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 - Softcover

Softcover

ISBN 10: 3038424129 ISBN 13: 9783038424123

Verlag: MDPI, 2017

Inhaltsangabe

The 8th International Conference on Protein Kinase CK2 (www.uks.eu/ck2), organized by Matthias Montenarh and Claudia Götz, will be held at the Faculty of Medicine of Saarland University, in Homburg, Germany, from 6–9 September, 2016. Protein kinase CK2 is a serine/threonine kinase, which is highly conserved in evolution. Knock-out experiments have shown that this enzyme is absolutely necessary for cell viability. The enzyme is highly expressed in rapidly proliferating cells, which goes along with an elevated enzyme activity. Protein kinase CK2 is involved in a broad range of signaling pathways, regulating proliferation, differentiation, apoptosis, or senescence. Recent advances towards the characterization of the three-dimensional structure of protein kinase CK2 and its subunits will undoubtedly yield important new insights into its regulation, and the functions of CK2. Moreover, with two inhibitors of the enzyme presently in clinical phase II trials, human protein kinase CK2 has appeared as an emerging target for cancer diseases.

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Über die Autorinnen und Autoren

PharmaCampus Institute of Pharmaceutical and Medicinal Chemistry, Westfälische Wilhelms-Universität, Corrensstr. 48, 48149, Muenster, Germany

EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie―ISPB, Université Lyon 1, Université de Lyon, SFR Santé Lyon-Est CNRS UMS3453―INSERM US7, 69373 Lyon cedex 8, France

Department of Biomedical Sciences, University of Padova, Via Ugo Bassi 58B, 35131 Padova, Italy

Medizinische Biochemie und Molekularbiologie, Faculty of Medicine, Saarland University Geb. 44/45, D-66424 Homburg, Germany

Details zur Ausgabe

• Verlag: MDPI
• Erscheinungsdatum: 2017
• Sprache: Englisch
• ISBN 10: 3038424129
• ISBN 13: 9783038424123
• Einband: Taschenbuch
• Anzahl der Seiten: 320
• Herausgeber: Jose Joachim, Le Borgne Marc, Pinna Lorenzo A., Montenarh Mathias
• Kontakt zum Hersteller: preigu GmbH & Co. KG; mail@preigu.de; ; Lengericher Landstr. 19; Osnabrück; Niedersachsen; 49078; Deutschland