The Identification of the Genetic Components of Autism Spectrum Disorders 2017 - Softcover

Softcover

ISBN 10: 3038425206 ISBN 13: 9783038425205

Verlag: MDPI, 2017

Inhaltsangabe

This textbook is dedicated to the study of genetic factors contributing to autism and includes a collection of original research and review articles related to this topic. Autism spectrum disorders (ASD) include a collection of neurodevelopmental disorders characterized by three recognized behavioral domains involving difficulties in communication, social interaction and repetitive behavior. ASD affects 1 to 2 percent of children and is on the increase worldwide. Significant genetic contributions and mechanisms underlie the causation of ASD. Advances in genetic technology and better awareness have led to a diagnosis of 50 to 70 percent of individuals with ASD primarily due to chromosomal abnormalities, submicroscopic deletions or duplications now identified with high-resolution microarray analysis, next-generation DNA (exome) sequencing of gene variants or mutations, recognized single gene disorders or metabolic disturbances. Through discovery by searching genomic databases and peer-reviewed research articles, nearly 800 genes have been identified to contribute to ASD. Highlights in the field of autism research, discovery and identification of genetic components with characterization will be addressed. Furthermore, reviews of current understanding of the causes and diagnostic approaches for ASD and related syndromes will be presented along with discussion of psychiatric/behavior comorbidities and related features, environmental risk factors, parental attitudes and treatment.

Über diesen Titel

Über die Autorin bzw. den Autor

The University of Kansas Medical Center USA

Details zur Ausgabe

• Verlag: MDPI
• Erscheinungsdatum: 2017
• Sprache: Englisch
• ISBN 10: 3038425206
• ISBN 13: 9783038425205
• Einband: Taschenbuch
• Auflage: 1
• Anzahl der Seiten: 474
• Herausgeber: Butler Merlin G.
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: preigu; mail@preigu.de; ; Lengericher Landstr. 19; Osnabrück; 49078; Deutschland