Zacarías León's thesis describes the development and validation of analytical methods to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products. León describes these methods in both in vitro and non-invasive in vivo methodologies. Currently dermatologists recommend the use of sunscreen products not only under conditions of extreme exposure to the sun but also in daily situations. However the chemical compounds in these products contain may lead to undesired processes and cause induced toxicity, estrogenic effects and endocrine activity. León establishes methods to investigate these effects and provides valuable information on the undesired side effects associated with the use of UV filters found in sunscreen products. The work in this thesis has led to a number of publications in renowned analytical chemistry journals.
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Zacarías León obtained his PhD in 2012 from the University of Valencia (Spain). His research has been focused on bioanalytical chemistry (i.e., body disposition of cosmetic ingredients), using mainly liquid and gas chromatography techniques with mass spectrometry detection. His current research interests are both targeted and untargeted metabolomics, including structural elucidation chemistry, drug metabolism and biomarker discovery.
Zacarías León's thesis describes the development and validation of analytical methods to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products. León describes these methods in both in vitro and non-invasive in vivo methodologies. Currently dermatologists recommend the use of sunscreen products not only under conditions of extreme exposure to the sun but also in daily situations. However the chemical compounds in these products contain may lead to undesired processes and cause induced toxicity, estogenic effects and endocrine activity. León establishes methods to investigate these effects and provides valuable information on the undesired side effects associated with the use of UV filters found in sunscreen products. The work in this thesis has led to a number of publications in renowned analytical chemistry journals.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Zacarías León's thesis describes the development and validation of analytical methods to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products. León describes these methods in both in vitro and non-invasive in vivo methodologies. Currently dermatologists recommend the use of sunscreen products not only under conditions of extreme exposure to the sun but also in daily situations. However the chemical compounds in these products contain may lead to undesired processes and cause induced toxicity, estrogenic effects and endocrine activity. León establishes methods to investigate these effects and provides valuable information on the undesired side effects associated with the use of UV filters found in sunscreen products. The work in this thesis has led to a number of publications in renowned analytical chemistry journals. 236 pp. Englisch. Bestandsnummer des Verkäufers 9783319011882
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Gebunden. Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Nominated as an outstanding Ph.D. thesis by the University of Valencia, Spain Presents a comprehensive review of the literatureProvides detailed information on in vitro and non-invasive in vivo percutaneous absorption studiesIncludes. Bestandsnummer des Verkäufers 4496077
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