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Rapid Cell Magnetisation Using Cationised Magnetoferritin (Springer Theses) - Softcover

Buch 293 von 797: Springer Theses

Correia Carreira, Sara

 
9783319868387: Rapid Cell Magnetisation Using Cationised Magnetoferritin (Springer Theses)
Softcover
ISBN 10: 3319868381 ISBN 13: 9783319868387
Verlag: Springer, 2018

Inhaltsangabe

Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently. 

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Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.

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Verlag
Springer
Erscheinungsdatum
2018
Sprache
Englisch
ISBN 10 
3319868381
ISBN 13 
9783319868387
Einband
Taschenbuch
Anzahl der Seiten
184
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9783319603322: Rapid Cell Magnetisation Using Cationised Magnetoferritin (Springer Theses)

Vorgestellte Ausgabe

ISBN 10:  3319603329 ISBN 13:  9783319603322
Verlag: Springer, 2017
Hardcover