Joint Modeling of Longitudinal CD4 Cell: Count Measurements and Time-to- Default from Highly Active Antiretroviral Therapy (HAART): a Comparison of Separate and Joint Models - Softcover
Inhaltsangabe
Even if the beneficial effect of HAART, increasing survival and the prevention of AIDS defining illness are well established, many patients are defaulting from the treatment. Such defaulter patients are at high risk of illness and death. Therefore, defaulting is a critical issue that needs to be addressed so that maximum benefit from HAART can be obtained. In such follow-up and other clinical trials, both longitudinal and survival data are generated. Hence, joint models are used to describe the joint behaviour of a biomarker (longitudinal response) process and an associated survival process. The objective of the study is to compare separate and joint models of longitudinal CD4 cells measurements and default time processes of HIV/AIDS patients under HAART treatment using a Bayesian approach. The results of the separate and joint models are consistent. When the joint model is compared with the separate model, it is both the most parsimonious model and also fits the data better than the separate model. The final joint model relates hazard of defaulting to two characteristics of the repeated CD4 measurements; patient-specific slopes and CD4 variability.
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Über die Autorin bzw. den Autor
Awol Seid Ebrie graduated from Jimma University.
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Joint Modeling of Longitudinal CD4 Cell
Verlag:
LAP LAMBERT Academic Publishing Apr 2018, 2018
ISBN 10: 3330050888
ISBN 13: 9783330050884
Neu
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Even if the beneficial effect of HAART, increasing survival and the prevention of AIDS defining illness are well established, many patients are defaulting from the treatment. Such defaulter patients are at high risk of illness and death. Therefore, defaulting is a critical issue that needs to be addressed so that maximum benefit from HAART can be obtained. In such follow-up and other clinical trials, both longitudinal and survival data are generated. Hence, joint models are used to describe the joint behaviour of a biomarker (longitudinal response) process and an associated survival process. The objective of the study is to compare separate and joint models of longitudinal CD4 cells measurements and default time processes of HIV/AIDS patients under HAART treatment using a Bayesian approach. The results of the separate and joint models are consistent. When the joint model is compared with the separate model, it is both the most parsimonious model and also fits the data better than the separate model. The final joint model relates hazard of defaulting to two characteristics of the repeated CD4 measurements; patient-specific slopes and CD4 variability. 80 pp. Englisch. Bestandsnummer des Verkäufers 9783330050884
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Joint Modeling of Longitudinal CD4 Cell
Verlag:
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3330050888
ISBN 13: 9783330050884
Neu
Softcover
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Seid AwolAwol Seid Ebrie graduated from Jimma University.Even if the beneficial effect of HAART, increasing survival and the prevention of AIDS defining illness are well established, many patients are defaulting from the treatmen. Bestandsnummer des Verkäufers 385707681
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Joint Modeling of Longitudinal CD4 Cell
Verlag:
LAP LAMBERT Academic Publishing Apr 2018, 2018
ISBN 10: 3330050888
ISBN 13: 9783330050884
Neu
Taschenbuch
Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland
Verkäuferbewertung 5 von 5 Sternen
Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Even if the beneficial effect of HAART, increasing survival and the prevention of AIDS defining illness are well established, many patients are defaulting from the treatment. Such defaulter patients are at high risk of illness and death. Therefore, defaulting is a critical issue that needs to be addressed so that maximum benefit from HAART can be obtained. In such follow-up and other clinical trials, both longitudinal and survival data are generated. Hence, joint models are used to describe the joint behaviour of a biomarker (longitudinal response) process and an associated survival process. The objective of the study is to compare separate and joint models of longitudinal CD4 cells measurements and default time processes of HIV/AIDS patients under HAART treatment using a Bayesian approach. The results of the separate and joint models are consistent. When the joint model is compared with the separate model, it is both the most parsimonious model and also fits the data better than the separate model. The final joint model relates hazard of defaulting to two characteristics of the repeated CD4 measurements; patient-specific slopes and CD4 variability.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 80 pp. Englisch. Bestandsnummer des Verkäufers 9783330050884
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Joint Modeling of Longitudinal CD4 Cell : Count Measurements and Time-to- Default from Highly Active Antiretroviral Therapy (HAART): a Comparison of Separate and Joint Models
Verlag:
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3330050888
ISBN 13: 9783330050884
Neu
Taschenbuch
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Even if the beneficial effect of HAART, increasing survival and the prevention of AIDS defining illness are well established, many patients are defaulting from the treatment. Such defaulter patients are at high risk of illness and death. Therefore, defaulting is a critical issue that needs to be addressed so that maximum benefit from HAART can be obtained. In such follow-up and other clinical trials, both longitudinal and survival data are generated. Hence, joint models are used to describe the joint behaviour of a biomarker (longitudinal response) process and an associated survival process. The objective of the study is to compare separate and joint models of longitudinal CD4 cells measurements and default time processes of HIV/AIDS patients under HAART treatment using a Bayesian approach. The results of the separate and joint models are consistent. When the joint model is compared with the separate model, it is both the most parsimonious model and also fits the data better than the separate model. The final joint model relates hazard of defaulting to two characteristics of the repeated CD4 measurements; patient-specific slopes and CD4 variability. Bestandsnummer des Verkäufers 9783330050884
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Joint Modeling of Longitudinal CD4 Cell | Count Measurements and Time-to- Default from Highly Active Antiretroviral Therapy (HAART): a Comparison of Separate and Joint Models
Verlag:
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3330050888
ISBN 13: 9783330050884
Neu
Taschenbuch
Anbieter: preigu, Osnabrück, Deutschland
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Taschenbuch. Zustand: Neu. Joint Modeling of Longitudinal CD4 Cell | Count Measurements and Time-to- Default from Highly Active Antiretroviral Therapy (HAART): a Comparison of Separate and Joint Models | Awol Seid | Taschenbuch | 80 S. | Englisch | 2018 | LAP LAMBERT Academic Publishing | EAN 9783330050884 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 113700408
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