A Nano delivery Approach: Development of Atorvastatin Nanoformulation - Softcover

Kalsyan, Rita; Raj, Vinit; Sahdev, Anil K.

 
9783330062467: A Nano delivery Approach: Development of Atorvastatin Nanoformulation
Softcover
ISBN 10: 3330062460 ISBN 13: 9783330062467
Verlag: LAP LAMBERT Academic Publishing, 2017

Inhaltsangabe

As we aware that Atorvastatin is BCS (Class II) drug and has poor solubility, extreme first pass metabolism and thus has poor bioavailability; on keeping in mind of all that factors we have to select that route which minimize all these effects and such formulation which deliver the drug to brain as much as possible. Hence we select intranasal route it offers direct access of drug to brain through olfactory route and avoid first pass metabolism and is suitable to deliver drugs via nanoformulation and have previously been utilized for enhanced brain delivery. NLC formulation could be able to deliver atorvastatin conveniently by intranasal route. NLC are nano sized delivery systems used to deliver drugs via intranasal route in different disease conditions. Their utility in intranasal route has been well documented. They can be suitably modified for improved retention and can cross mucosal barrier.

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Über die Autorin bzw. den Autor

Rita Kalsyan: ICP, Greater Noida, India.Anil K Sahdev and Vinit Raj:Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2017
Sprache
Englisch
ISBN 10 
3330062460
ISBN 13 
9783330062467
Einband
Taschenbuch
Anzahl der Seiten
92
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
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Brivibas gatve 197
Riga
1039
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