Molecular Drug Properties: Measurement and Prediction (Methods and Principles in Medicinal Chemistry, 37, Band 37) - Hardcover
Inhaltsangabe
This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, electronic properties and conformation.
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Über die Autorin bzw. den Autor
Raimund Mannhold is Professor for Molecular Drug Research at the University of Düsseldorf, Germany. His scientific interests lie with QSAR studies and related methods to determine and predict drug properties. He is a founding editor of the book series 'Methods and Principles in Medicinal Chemistry' and serves on the editorial boards of several journals in the field of medicinal chemistry and drug design.
Von der hinteren Coverseite
This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates.
Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity, solubility, electronic properties and conformation. Finally, it is shown how physico-chemical drug properties guide drug- and lead-likeness.
Aus dem Klappentext
This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates.
Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity, solubility, electronic properties and conformation. Finally, it is shown how physico-chemical drug properties guide drug- and lead-likeness.
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MOLECULAR DRUG PROPERTIES: Measurement and Prediction
Verlag:
Wiley - VCH, 2008
ISBN 10: 3527317554
ISBN 13: 9783527317554
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Hardcover
Erstausgabe
Anbieter: Frey Fine Books, Rougemont, NC, USA
Verkäuferbewertung 5 von 5 Sternen
Hardcover. Zustand: Near Fine. 1st edition. 1st edition. A Near Fine copy. 4to., xxx, 471 pp., illustrated with charts,graphs, and diagrams. Bound in white with blue spine, glossy, paper boards. Part of the publisher's series, Methods and Principles in Medicinal Chemistry, this being volume 37 in that series. Bestandsnummer des Verkäufers 32661
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