Interstitial Cells of Cajal: Intestinal Pacemaker Cells?: 71 (Advances in Anatomy, Embryology and Cell Biology) - Softcover

Thuneberg, Lars

 
9783540112617: Interstitial Cells of Cajal: Intestinal Pacemaker Cells?: 71 (Advances in Anatomy, Embryology and Cell Biology)
Softcover
ISBN 10: 3540112618 ISBN 13: 9783540112617
Verlag: Springer Berlin Heidelberg, 1982

Inhaltsangabe

In 1949, the Dutch anatomist Jan Boeke was able to write: "The socalled interstitial cells . . . which lie at the end of the sympathetic endformation as a connecting link between the nervous endformation and the effector cells, are . . . shown to be of pri­ mary importance for the transferring and the remoulding of the nervous stimulus . . . . " And: " . . . the problem of the interstitial cells and of the synapse is the most impor­ tant problem of neurohistology of the future. " When Boeke wrote this, he advocated the generalized concept, holding that inter­ stitial cells were intercalated between autonomic nerves and effector cells. A frank illus­ tration of this is presented by Tinel (l937), who places interstitial cells of Cajal (ICC) as terminal neurons of all autonomic nerves (his Fig. 1). While there have been over 100 light microscopic investigations (Table 1) of ICC in tissues and organs other than intestine, none of these have been followed up by electron microscopic studies. It is important to bear in mind that when the term ICC is used today, the only reference tissue for which sufficient information (i. e. , including an ultrastructural identification) on the ICC is at hand is the intestine, or rather the muscularis externa of small inte­ stine (in Table 1, those contributions which relate to intestinal ICC are underlined).

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Reseña del editor

In 1949, the Dutch anatomist Jan Boeke was able to write: "The socalled interstitial cells . . . which lie at the end of the sympathetic endformation as a connecting link between the nervous endformation and the effector cells, are . . . shown to be of pri­ mary importance for the transferring and the remoulding of the nervous stimulus . . . . " And: " . . . the problem of the interstitial cells and of the synapse is the most impor­ tant problem of neurohistology of the future. " When Boeke wrote this, he advocated the generalized concept, holding that inter­ stitial cells were intercalated between autonomic nerves and effector cells. A frank illus­ tration of this is presented by Tinel (l937), who places interstitial cells of Cajal (ICC) as terminal neurons of all autonomic nerves (his Fig. 1). While there have been over 100 light microscopic investigations (Table 1) of ICC in tissues and organs other than intestine, none of these have been followed up by electron microscopic studies. It is important to bear in mind that when the term ICC is used today, the only reference tissue for which sufficient information (i. e. , including an ultrastructural identification) on the ICC is at hand is the intestine, or rather the muscularis externa of small inte­ stine (in Table 1, those contributions which relate to intestinal ICC are underlined).

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Verlag
Springer Berlin Heidelberg
Erscheinungsdatum
1982
Sprache
Englisch
ISBN 10 
3540112618
ISBN 13 
9783540112617
Einband
Tapa blanda
Anzahl der Seiten
144
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
CMN Printpool Inh. Mathis Neumann
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Hamburg
Deutschland

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9780387112619: Intestinal Pacemaker Cells: 71 (Advances in Anatomy, Embryology & Cell Biology)

Vorgestellte Ausgabe

ISBN 10:  0387112618 ISBN 13:  9780387112619
Verlag: Springer Verlag, 1982
Softcover