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Cell Adhesion: 165 (Handbook of Experimental Pharmacology) - Hardcover

 
9783540209416: Cell Adhesion: 165 (Handbook of Experimental Pharmacology)

Inhaltsangabe

As with other areas of biological research, the progress that has been made over the past 25 years in the field of cell adhesion is impressive. In the late 1970s, the searchfor specific cell surface receptors for adhesion processes was initiated - ing mainly biochemical and immunological approaches. Since then, theint- duction of novel methods of cellular and molecular biology and powerful te- niques for manipulatinggene expression in transgenic and knock-out mice have greatlyadvanced the field. Not only dowe now know the precise molecular structure of many of thecell adhesion receptors that were postulated to exist in the early days, but we have a clear picture of their function, and evidence of their involvement in signal transduction. We have also found clues to the role of cell adhesion in normal embryonal development and adult physiology, and we have evidence that disturbance in cell adhesion can cause disease. In this volume, our goal was to provide an overview of the main topics of c- rent cell adhesion research, including structural analyses of cell adhesion mo- cules and studies of their functionalrole in vitroand in vivo. We have focussed mainly on the four major families of cell-adhesion receptors, i. e. the cadherins, the integrins, the Ig superfamily and the selectin-based adhesion system. The chapters by Perez and Nelson and Choi and Weis describethe structuralbasis of cadherin function, focussing on the extracellular domain of cadherins and thecytoplasmic tail interactions with catenins, respectively.

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Reseña del editor

As with other areas of biological research, the progress that has been made over the past 25 years in the field of cell adhesion is impressive. In the late 1970s, the searchfor specific cell surface receptors for adhesion processes was initiated - ing mainly biochemical and immunological approaches. Since then, theint- duction of novel methods of cellular and molecular biology and powerful te- niques for manipulatinggene expression in transgenic and knock-out mice have greatlyadvanced the field. Not only dowe now know the precise molecular structure of many of thecell adhesion receptors that were postulated to exist in the early days, but we have a clear picture of their function, and evidence of their involvement in signal transduction. We have also found clues to the role of cell adhesion in normal embryonal development and adult physiology, and we have evidence that disturbance in cell adhesion can cause disease. In this volume, our goal was to provide an overview of the main topics of c- rent cell adhesion research, including structural analyses of cell adhesion mo- cules and studies of their functionalrole in vitroand in vivo. We have focussed mainly on the four major families of cell-adhesion receptors, i. e. the cadherins, the integrins, the Ig superfamily and the selectin-based adhesion system. The chapters by Perez and Nelson and Choi and Weis describethe structuralbasis of cadherin function, focussing on the extracellular domain of cadherins and thecytoplasmic tail interactions with catenins, respectively.

Reseña del editor

This book provides an overview of the main topics of current cell adhesion research including structural analyses of cell adhesion molecules and studies to their functional role in vitro and in vivo. The present volume focuses on the four major families of cell-adhesion receptors, i. e. the cadherins, the integrins, the Ig-superfamily and the selectin-based adhesion system which are discussed in detail by numerous experts in the field.

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9783642058936: Cell Adhesion: 165 (Handbook of Experimental Pharmacology)

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ISBN 10:  3642058930 ISBN 13:  9783642058936
Verlag: Springer, 2010
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Jürgen Behrens; Warren James Nelson
Verlag: Springer, Germany, 2004
ISBN 10: 3540209417 ISBN 13: 9783540209416
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Hardcover. Zustand: Near Fine. No Jacket. 3540209417. Hardcover, from closed pharmaceutical company library. Lending record shows this book has been borrowed once only. Text in English. 481 pages, index, illustrated with charts, tables and diagrams. We know the molecular structure of many cell adhesion receptors, and have a clear picture of their function, and involvement in signal transduction. We also have clues to the role of cell adhesion in normal embryonal development and adult physiology, and we have evidence that disturbance in cell adhesion can cause disease. This volume presents an overview of the main topics of cell adhesion research, including structural analyses of cell adhesion molecules and studies of their functiona lrole in vitro and in vivo. Focussing on the four major families of cell-adhesion receptors: the cadherins, the integrins, the Ig superfamily and the selectin-based adhesion system. The chapters by Perez and Nelson and Choi and Weis describethe structura lbasis of cadherin function, focussing on the extracellular domain of cadherins and the cytoplasmic tail interactions with catenins, respectively. Contents clean, tight and bright. Book. Bestandsnummer des Verkäufers 024574

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Zustand: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,850grams, ISBN:9783540209416. Bestandsnummer des Verkäufers 9619664

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2004. 15 x 23 cm. X, 482 S. X, 482 p. 69 illus., 10 illus. in color. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. (Handbook of Experimental Pharmacology). Sprache: Englisch. Bestandsnummer des Verkäufers 289ZB

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Gebunden. Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Cadherins.- Cadherin Adhesion: Mechanisms and Molecular Interactions.- Structural Aspects of Adherens Junctions and Desmosomes.- Cadherins in Development.- Cadherins in Cancer.- In Vivo Functions of Catenins.- The Molecular Composition and Function of Desmo. Bestandsnummer des Verkäufers 4884926

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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - As with other areas of biological research, the progress that has been made over the past 25 years in the field of cell adhesion is impressive. In the late 1970s, the searchfor specific cell surface receptors for adhesion processes was initiated - ing mainly biochemical and immunological approaches. Since then, theint- duction of novel methods of cellular and molecular biology and powerful te- niques for manipulatinggene expression in transgenic and knock-out mice have greatlyadvanced the field. Not only dowe now know the precise molecular structure of many of thecell adhesion receptors that were postulated to exist in the early days, but we have a clear picture of their function, and evidence of their involvement in signal transduction. We have also found clues to the role of cell adhesion in normal embryonal development and adult physiology, and we have evidence that disturbance in cell adhesion can cause disease. In this volume, our goal was to provide an overview of the main topics of c- rent cell adhesion research, including structural analyses of cell adhesion mo- cules and studies of their functionalrole in vitroand in vivo. We have focussed mainly on the four major families of cell-adhesion receptors, i. e. the cadherins, the integrins, the Ig superfamily and the selectin-based adhesion system. The chapters by Perez and Nelson and Choi and Weis describethe structuralbasis of cadherin function, focussing on the extracellular domain of cadherins and thecytoplasmic tail interactions with catenins, respectively. Bestandsnummer des Verkäufers 9783540209416

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Buch. Zustand: Neu. Neuware -As with other areas of biological research, the progress that has been made over the past 25 years in the field of cell adhesion is impressive. In the late 1970s, the searchfor specific cell surface receptors for adhesion processes was initiated - ing mainly biochemical and immunological approaches. Since then, theint- duction of novel methods of cellular and molecular biology and powerful te- niques for manipulatinggene expression in transgenic and knock-out mice have greatlyadvanced the field. Not only dowe now know the precise molecular structure of many of thecell adhesion receptors that were postulated to exist in the early days, but we have a clear picture of their function, and evidence of their involvement in signal transduction. We have also found clues to the role of cell adhesion in normal embryonal development and adult physiology, and we have evidence that disturbance in cell adhesion can cause disease. In this volume, our goal was to provide an overview of the main topics of c- rent cell adhesion research, including structural analyses of cell adhesion mo- cules and studies of their functionalrole in vitroand in vivo. We have focussed mainly on the four major families of cell-adhesion receptors, i. e. the cadherins, the integrins, the Ig superfamily and the selectin-based adhesion system. The chapters by Perez and Nelson and Choi and Weis describethe structuralbasis of cadherin function, focussing on the extracellular domain of cadherins and thecytoplasmic tail interactions with catenins, respectively.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 492 pp. Englisch. Bestandsnummer des Verkäufers 9783540209416

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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As with other areas of biological research, the progress that has been made over the past 25 years in the field of cell adhesion is impressive. In the late 1970s, the searchfor specific cell surface receptors for adhesion processes was initiated - ing mainly biochemical and immunological approaches. Since then, theint- duction of novel methods of cellular and molecular biology and powerful te- niques for manipulatinggene expression in transgenic and knock-out mice have greatlyadvanced the field. Not only dowe now know the precise molecular structure of many of thecell adhesion receptors that were postulated to exist in the early days, but we have a clear picture of their function, and evidence of their involvement in signal transduction. We have also found clues to the role of cell adhesion in normal embryonal development and adult physiology, and we have evidence that disturbance in cell adhesion can cause disease. In this volume, our goal was to provide an overview of the main topics of c- rent cell adhesion research, including structural analyses of cell adhesion mo- cules and studies of their functionalrole in vitroand in vivo. We have focussed mainly on the four major families of cell-adhesion receptors, i. e. the cadherins, the integrins, the Ig superfamily and the selectin-based adhesion system. The chapters by Perez and Nelson and Choi and Weis describethe structuralbasis of cadherin function, focussing on the extracellular domain of cadherins and thecytoplasmic tail interactions with catenins, respectively. 492 pp. Englisch. Bestandsnummer des Verkäufers 9783540209416

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Berx, G. (EDT); Borradori, L. (CON); Brabletz, T. (CON); Bradfield, P. F. (CON); Choi, H. J. (CON); Getsios, S. (CON); Godsel, L. M. (CON); Green, K. J. (CON); Horst, A. K. (CON); Huen, A. C. (CON); Ikeda, W. (CON); Imhof, B. A. (CON); Irie, K. (CON); Juliano, R. L. (CON); Koster, J. (CON)
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Berx, G. (EDT); Borradori, L. (CON); Brabletz, T. (CON); Bradfield, P. F. (CON); Choi, H. J. (CON); Getsios, S. (CON); Godsel, L. M. (CON); Green, K. J. (CON); Horst, A. K. (CON); Huen, A. C. (CON); Ikeda, W. (CON); Imhof, B. A. (CON); Irie, K. (CON); Juliano, R. L. (CON); Koster, J. (CON)
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