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Stem Cell Proliferation and Differentiation: A Multitype Branching Process Model: 76 (Lecture Notes in Biomathematics, 76) - Softcover
Inhaltsangabe
The body contains many cellular systems that require the continuous production of new, fully functional, differentiated cells to replace cells lacking or having limited self-renewal capabilities that die or are damaged during the lifetime of an individual. Such systems include the epidermis, the epithelial lining of the gut, and the blood. For example, erythrocytes (red blood cells) lack nuclei and thus are incapable of self-replication. They have a life span in the circulation of about 120 days. Mature granulocytes, which also lack proliferative capacity, have a much shorter life span - typically 12 hours, though this may be reduced to only two or three hours in times of serious tissue infection. Perhaps a more familiar example is the outermost layer of the skin. This layer is composed of fully mature, dead epidermal cells that must be replaced by the descendants of stem cells lodged in lower layers of the epidermis (cf. Alberts et al. , 1983). In total, to supply the normal steady-state demands of cells, an average human must produce approximately 3. 7 x 1011 cells a day throughout life (Dexter and Spooncer, 1987). Common to each of these cellular systems is a primitive (undifferentiated) stem cell which replenishes cells through the production of offspring, some of which proliferate and gradually differentiate until mature, fully functional cells are produced.
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The body contains many cellular systems that require the continuous production of new, fully functional, differentiated cells to replace cells lacking or having limited self-renewal capabilities that die or are damaged during the lifetime of an individual. Such systems include the epidermis, the epithelial lining of the gut, and the blood. For example, erythrocytes (red blood cells) lack nuclei and thus are incapable of self-replication. They have a life span in the circulation of about 120 days. Mature granulocytes, which also lack proliferative capacity, have a much shorter life span - typically 12 hours, though this may be reduced to only two or three hours in times of serious tissue infection. Perhaps a more familiar example is the outermost layer of the skin. This layer is composed of fully mature, dead epidermal cells that must be replaced by the descendants of stem cells lodged in lower layers of the epidermis (cf. Alberts et al. , 1983). In total, to supply the normal steady-state demands of cells, an average human must produce approximately 3. 7 x 1011 cells a day throughout life (Dexter and Spooncer, 1987). Common to each of these cellular systems is a primitive (undifferentiated) stem cell which replenishes cells through the production of offspring, some of which proliferate and gradually differentiate until mature, fully functional cells are produced.
Reseña del editor
The book develops a model for stem cell proliferation and differentiation. It is a substantial generalization of the famous Till and McCulloch model. It describes the growth of stem cells in culture and the formation of both progenitor cells and end cells. The book contains a biologically realistic application of branching processes and should be of interest to mathematics students and teachers of stochastic process courses.
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Stem cell proliferation and differentiation. A multitype branching process model.
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Softcover. VIII, 113 S. Ehem. Bibliotheksexemplar mit Signatur und Stempel. GUTER Zustand, ein paar Gebrauchsspuren. Ex-library with stamp and library-signature. GOOD condition, some traces of use. C-01190 3540501835 Sprache: Englisch Gewicht in Gramm: 550. Bestandsnummer des Verkäufers 2485045
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Stem cell proliferation and differentiation : a multitype branching process model
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Broschiert. Zustand: Gut. 24,5 cm VIII, 113 S. : graph. Darst. ; Broschiert. Zustand: Gut; Leicht gebräunt (Innen); Einer Schrifteintrag auf dem Titelblatt; * Die Photos sind original von uns erstellt worden, u.a. erkennbar an einem kleinen weißen Stück Papier im oberen Schnitt. Ab und an verwenden Suchmaschinen Verlagsphotos, bei den Portalen selbst, werden aber nur unsere Originalphotos gezeigt. Bestandsnummer des Verkäufers 380752
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Stem Cell Proliferation and Differentiation
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The body contains many cellular systems that require the continuous production of new, fully functional, differentiated cells to replace cells lacking or having limited self-renewal capabilities that die or are damaged during the lifetime of an individual. . Bestandsnummer des Verkäufers 4891482
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Stem Cell Proliferation and Differentiation : A Multitype Branching Process Model
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The body contains many cellular systems that require the continuous production of new, fully functional, differentiated cells to replace cells lacking or having limited self-renewal capabilities that die or are damaged during the lifetime of an individual. Such systems include the epidermis, the epithelial lining of the gut, and the blood. For example, erythrocytes (red blood cells) lack nuclei and thus are incapable of self-replication. They have a life span in the circulation of about 120 days. Mature granulocytes, which also lack proliferative capacity, have a much shorter life span - typically 12 hours, though this may be reduced to only two or three hours in times of serious tissue infection. Perhaps a more familiar example is the outermost layer of the skin. This layer is composed of fully mature, dead epidermal cells that must be replaced by the descendants of stem cells lodged in lower layers of the epidermis (cf. Alberts et al. , 1983). In total, to supply the normal steady-state demands of cells, an average human must produce approximately 3. 7 x 1011 cells a day throughout life (Dexter and Spooncer, 1987). Common to each of these cellular systems is a primitive (undifferentiated) stem cell which replenishes cells through the production of offspring, some of which proliferate and gradually differentiate until mature, fully functional cells are produced. Bestandsnummer des Verkäufers 9783540501831
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Stem Cell Proliferation and Differentiation
ISBN 10: 3540501835
ISBN 13: 9783540501831
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The body contains many cellular systems that require the continuous production of new, fully functional, differentiated cells to replace cells lacking or having limited self-renewal capabilities that die or are damaged during the lifetime of an individual. Such systems include the epidermis, the epithelial lining of the gut, and the blood. For example, erythrocytes (red blood cells) lack nuclei and thus are incapable of self-replication. They have a life span in the circulation of about 120 days. Mature granulocytes, which also lack proliferative capacity, have a much shorter life span - typically 12 hours, though this may be reduced to only two or three hours in times of serious tissue infection. Perhaps a more familiar example is the outermost layer of the skin. This layer is composed of fully mature, dead epidermal cells that must be replaced by the descendants of stem cells lodged in lower layers of the epidermis (cf. Alberts et al. , 1983). In total, to supply the normal steady-state demands of cells, an average human must produce approximately 3. 7 x 1011 cells a day throughout life (Dexter and Spooncer, 1987). Common to each of these cellular systems is a primitive (undifferentiated) stem cell which replenishes cells through the production of offspring, some of which proliferate and gradually differentiate until mature, fully functional cells are produced.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 128 pp. Englisch. Bestandsnummer des Verkäufers 9783540501831
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Stem Cell Proliferation and Differentiation
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Springer Berlin Heidelberg Okt 1988, 1988
ISBN 10: 3540501835
ISBN 13: 9783540501831
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The body contains many cellular systems that require the continuous production of new, fully functional, differentiated cells to replace cells lacking or having limited self-renewal capabilities that die or are damaged during the lifetime of an individual. Such systems include the epidermis, the epithelial lining of the gut, and the blood. For example, erythrocytes (red blood cells) lack nuclei and thus are incapable of self-replication. They have a life span in the circulation of about 120 days. Mature granulocytes, which also lack proliferative capacity, have a much shorter life span - typically 12 hours, though this may be reduced to only two or three hours in times of serious tissue infection. Perhaps a more familiar example is the outermost layer of the skin. This layer is composed of fully mature, dead epidermal cells that must be replaced by the descendants of stem cells lodged in lower layers of the epidermis (cf. Alberts et al. , 1983). In total, to supply the normal steady-state demands of cells, an average human must produce approximately 3. 7 x 1011 cells a day throughout life (Dexter and Spooncer, 1987). Common to each of these cellular systems is a primitive (undifferentiated) stem cell which replenishes cells through the production of offspring, some of which proliferate and gradually differentiate until mature, fully functional cells are produced. 128 pp. Englisch. Bestandsnummer des Verkäufers 9783540501831
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Stem Cell Proliferation and Differentiation: A Multitype Branching Process Model (Lecture Notes in Biomathematics, 76)
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Stem Cell Proliferation and Differentiation : A Multitype Branching Process Model
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Stem Cell Proliferation and Differentiation: A Multitype Branching Process Model (Lecture Notes in Biomathematics, 76)
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Stem Cell Proliferation and Differentiation: A Multitype Branching Process Model (Lecture Notes in Biomathematics, 76)
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