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Structure-Based Drug Design: Thermodynamics, Modeling and Strategy (Biotechnology Intelligence Unit) - Hardcover
Inhaltsangabe
This book connects two subjects: "drug design" - a biological science - and "thermodynamics" - a physical science. Armed with the knowledge of the three-dimensional structure of a potential binding site of a molecule, the method of structure-based design provides a rapid, rational route to a ligand molecule. Recent developments in the determination of structure and the measurement of thermodynamic parameters of binding have resulted in drawing theoretical and experimental data together to improve our ability to model these interactions de novo. This book presents the state of the art and outlines future developments in the field of structure-based ligand design.
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