DNA Methylation and Cancer (Current Topics in Microbiology and Immunology, Band 249) - Hardcover

Buch 73 von 322: Current Topics in Microbiology and Immunology
 
9783540666080: DNA Methylation and Cancer (Current Topics in Microbiology and Immunology, Band 249)
Hardcover
ISBN 10: 3540666087 ISBN 13: 9783540666080
Verlag: Springer, 2000

Inhaltsangabe

This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer. Issues related to the mutagenicity of 5-methylcytosine and the increase in the interaction of chemical and physical carcinogens with these residues is discussed. The book summarizes the modulation of viral gene expression and the silencing of tumor suppressor genes and illustrates mechanisms by which the methylation signal is translated into altered chromatin structure. The relationship between DNA methylation and genomic imprinting and cancer, and changes in CpG island methylation which occur in aging are discussed. Mouse model systems have played a key role in our dissection of the relationship between methylation and cancer, and these are also portrayed together with descriptions of new clinical trials in which methylation inhibitors are being used to treat leukemia, myeloid dysplastic syndromes and hemoglobinopathies.

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Verlag
Springer
Erscheinungsdatum
2000
Sprache
Englisch
ISBN 10 
3540666087
ISBN 13 
9783540666080
Einband
Gebundene Ausgabe
Auflage
1
Anzahl der Seiten
180
Herausgeber
Jones P.A., Vogt P.K.
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Deutschland

Weitere beliebte Ausgaben desselben Titels

9783642640902: DNA Methylation and Cancer (Current Topics in Microbiology and Immunology, Band 249)

Vorgestellte Ausgabe

ISBN 10:  3642640907 ISBN 13:  9783642640902
Verlag: Springer, 2011
Softcover