Clostridium difficile (Current Topics in Microbiology and Immunology, Band 250) - Softcover

Buch 64 von 322: Current Topics in Microbiology and Immunology
 
9783642086687: Clostridium difficile (Current Topics in Microbiology and Immunology, Band 250)
Softcover
ISBN 10: 3642086683 ISBN 13: 9783642086687
Verlag: Springer, 2010

Inhaltsangabe

Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of Clostridium difficile and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to Clostridium difficile toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the prototypes of a new family of large clostridial cytotoxins is described in great detail. Clostridium difficile toxins act as glucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes.

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Verlag
Springer
Erscheinungsdatum
2010
Sprache
Englisch
ISBN 10 
3642086683
ISBN 13 
9783642086687
Einband
Taschenbuch
Anzahl der Seiten
160
Herausgeber
Aktories K., Wilkins T.D.
Kontakt zum Hersteller
ProductSafety@springernature.com
ProductSafety@springernature.com

Poststr. 9
Darmstadt
64293
Deutschland

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Hardcover