Sparking Signals: Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation: 2007/3 (Ernst Schering Foundation Symposium Proceedings) - Softcover

Softcover

ISBN 10: 3642092624 ISBN 13: 9783642092626

Verlag: Springer, 2010

Inhaltsangabe

Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.

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Reseña del editor

The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. In this book, well known experts present their most recent findings on the fast developing kinase field. It will be of interest to basic researchers and the pharmaceutical industry.

Details zur Ausgabe

• Verlag: Springer
• Erscheinungsdatum: 2010
• Sprache: Englisch
• ISBN 10: 3642092624
• ISBN 13: 9783642092626
• Einband: Tapa blanda
• Anzahl der Seiten: 204
• Herausgeber: Baier Gottfried, Schraven Burkhart, Zügel Ulrich, Bonin Arne
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Deutschland