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Cancer Immunology and Immunotherapy: 344 (Current Topics in Microbiology and Immunology) - Hardcover
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“This book comprises 13 reviews, contributed by members of a cross-section of groups working in the ... field of cancer immunology. ... this book is at its best when considering small and apparently discrete topics – its strength comes from being able to read all of these ideas on one place. ... Overall, this book gives a thorough and detailed overview of the current state of basic and translational research into cancer immunology ... . It’s probably most appropriate for researchers ... .” (Victoria Lawson, Immunology News, November, 2011)The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
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- VerlagSpringer
- Erscheinungsdatum2011
- ISBN 10 3642141358
- ISBN 13 9783642141355
- EinbandTapa dura
- Anzahl der Seiten320
- HerausgeberDranoff Glenn
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Cancer Immunology and Immunotherapy (Current Topics in Microbiology and Immunology, 344)
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Buchbeschreibung Hardcover. Zustand: new. New. Fast Shipping and good customer service. Bestandsnummer des Verkäufers Holz_New_3642141358
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Cancer Immunology and Immunotherapy (Current Topics in Microbiology and Immunology) [Hardcover ]
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Buchbeschreibung Hardcover. Zustand: new. Bestandsnummer des Verkäufers 9783642141355
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Cancer Immunology and Immunotherapy (Current Topics in Microbiology and Immunology, 344)
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Cancer Immunology and Immunotherapy
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Springer Berlin Heidelberg
(2011)
ISBN 10: 3642141358
ISBN 13: 9783642141355
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Buchbeschreibung Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tu. Bestandsnummer des Verkäufers 5050410
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Cancer Immunology and Immunotherapy
Verlag:
Springer Berlin Heidelberg Apr 2011
(2011)
ISBN 10: 3642141358
ISBN 13: 9783642141355
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Buchbeschreibung Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment. 320 pp. Englisch. Bestandsnummer des Verkäufers 9783642141355
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Cancer Immunology and Immunotherapy
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Buchbeschreibung Zustand: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Bestandsnummer des Verkäufers ria9783642141355_lsuk
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Cancer Immunology and Immunotherapy
Verlag:
Springer Berlin Heidelberg
(2011)
ISBN 10: 3642141358
ISBN 13: 9783642141355
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Hardcover
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Buchbeschreibung Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment. Bestandsnummer des Verkäufers 9783642141355
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