Epoxidations and Hydroperoxidations of α,β-Unsaturated Ketones: An Approach through Asymmetric Organocatalysis (Springer Theses) - Hardcover

Reisinger, Corinna

Hardcover

ISBN 10: 3642281176 ISBN 13: 9783642281174

Verlag: Springer, 2012

Inhaltsangabe

Book by Reisinger Corinna

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Reseña del editor:

Corinna Reisinger has developed a new organocatalytic asymmetric epoxidation of cyclic and acyclic α,β-unsaturated ketones. In this thesis, Corinna documents her methodology, using primary amine salts as catalysts, and hydrogen peroxide as an inexpensive and environmentally benign oxidant. She describes the unprecedented and powerful catalytic asymmetric hydro­peroxi­dation of α,β-enones, a process which produces optically active five-membered cyclic peroxyhemiketals in a single operation. She also proves the versatility and synthetic value of the cyclic peroxyhemiketals by converting them into highly enantioenriched acyclic and cyclic aldol products. Currently, these cyclic aldol products are inaccessible by any other synthetic means. Furthermore, cyclic peroxyhemiketals are precursors to optically active 1,2-dioxolanes which are of biological relevance. This work is a breakthrough in the field of asymmetric epoxidation chemistry and outlines the most efficient method in the literature for generating highly enantioselective cyclic epoxyketones known to date.

Biografía del autor:

Dr. Corinna Reisinger Evonik AG corinna.reisinger@web.de

Über diese Auflage

• Verlag: Springer
• Erscheinungsdatum: 2012
• ISBN 10: 3642281176
• ISBN 13: 9783642281174
• Einband: Tapa dura
• Anzahl der Seiten: 276