Intrinsic Immunity (Current Topics in Microbiology and Immunology, 371, Band 371) - Hardcover

Buch 216 von 322: Current Topics in Microbiology and Immunology
 
9783642377648: Intrinsic Immunity (Current Topics in Microbiology and Immunology, 371, Band 371)
Hardcover
ISBN 10: 3642377645 ISBN 13: 9783642377648
Verlag: Springer, 2013

Inhaltsangabe

Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted.

 

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Verlag
Springer
Erscheinungsdatum
2013
Sprache
Englisch
ISBN 10 
3642377645
ISBN 13 
9783642377648
Einband
Gebundene Ausgabe
Anzahl der Seiten
269
Herausgeber
Cullen Bryan R.
Kontakt zum Hersteller
ProductSafety@springernature.com
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Poststr. 9
Darmstadt
64293
Deutschland

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ISBN 10:  3642427634 ISBN 13:  9783642427633
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Softcover