Specificity, Function, and Development of NK Cells: NK Cells: The Effector Arm of Innate Immunity (Current Topics in Microbiology and Immunology, Band 230) - Softcover

Buch 300 von 322: Current Topics in Microbiology and Immunology
 
9783642468612: Specificity, Function, and Development of NK Cells: NK Cells: The Effector Arm of Innate Immunity (Current Topics in Microbiology and Immunology, Band 230)
Softcover
ISBN 10: 3642468616 ISBN 13: 9783642468612
Verlag: Springer, 2012

Inhaltsangabe

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.

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Verlag
Springer
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
3642468616
ISBN 13 
9783642468612
Einband
Taschenbuch
Anzahl der Seiten
264
Herausgeber
Kärre Klas, Colonna Marco
Kontakt zum Hersteller
ProductSafety@springernature.com
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Deutschland

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