Inhaltsangabe
1 Introduction.- 2 Thymidine Labeling as an Indication of Cell Proliferation.- 3 Period of Proliferation of Different Cell Types in the Rat and Mouse Brain.- 3.1 Methods.- 3.2 Period of Proliferation.- 3.2.1 Neurons.- 3.2.2 Neuroglia (Astrocytes, Oligodendrocytes).- 3.2.3 Cells of the Subependymal Layer.- 3.2.4 Ependymal Cells.- 3.2.5 Epithelial Cells of the Choroid Plexus.- 3.2.6 Endothelial Cells.- 3.2.7 Microglia and Pericytes.- 3.2.8 Meningeal Cells.- 3.2.9 Graphic Summary of the Proliferation of the Different Cell Types.- 4 Cell Cycle Parameters of the Different Cell Types in the Rodent Brain During Pre- and Postnatal Ontogeny.- 4.1 Methods for the Experimental Determination of Cell Cycle Parameters.- 4.1.1 Percent Labeled Mitoses Method.- 4.1.2 Continuous Infusion with 3H-Thymidine.- 4.1.3 Grain-Count Halving Method.- 4.1.4 Double-Labeling Methods with 3H- and 14C-TdR.- 4.2 Methods of Calculating Cell Cycle Parameters.- 4.2.1 Mean Cycle Time.- 4.2.2 Turnover Time.- 4.2.3 Growth Fraction.- 4.3 Compilation of Cell Cycle Parameters.- 5 Mode of Proliferation.- 5.1 Proliferation with Cell Loss.- 5.1.1 Pyknotic Neuroglial Cells.- 5.1.2 Pyknotic Cells of the Subependymal Layer.- 5.1.3 Pyknotic Precursor Cells of Neurons.- 5.1.4 Pyknotic Endothelial Cells.- 5.2 Proliferation with Exchange of Cells between the Growth Fraction and Nongrowth Fraction.- 5.2.1 Neuroglia.- 5.2.2 Endothelial Cells.- 5.2.3 Cells of the Subependymal Layer.- 5.2.4 Neurons.- 5.2.5 Ependymal Cells and Epithelial Cells of the Choroid Plexus.- 5.2.6 Microglia and Pericytes.- 5.3 Comparison of the Mode of Proliferation of Various Cell Types During Pre- and Postnatal Ontogeny.- 6 Summary.- References.
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