Protein Structure and Protein Engineering: 39 (Colloquium der Gesellschaft für Biologische Chemie in Mosbach Baden) - Softcover

Softcover

ISBN 10: 3642741754 ISBN 13: 9783642741753

Verlag: Springer, 2013

Über diesen Titel

Reseña del editor

Protein engineering has had considerable impact on basic and applied research in biochemistry and molecular biology. It is already in use as a tool in molecular biology, but it is beginning to strongly influence the planning of experiments in biology everywhere, and, with even fur­ ther-reaching consequences, the appointment politics in research in­ stitutions and industries. Protein engineering, perhaps more than any other methods of protein analysis and peptide synthesis, has shown that proteins are organic molecules governed by the universal laws of chemistry and physics. How­ ever, as was the case with other new powerful methods and techniques, protein engineering tempts to an exploration of its limitations and thus generates more questions than it answers. The 39th Mosbacher Colloquium on Protein Structure and Protein Engi­ neering is not the first conference on this topic and it will not be the last. The important issues are obviously techniques of protein en­ gineering, examples of application, and the basic framework of protein structure and stability within which reasonable experiments can be de­ signed; conversely also, what we can learn about protein structure, dynamics, and folding from such experiments. Experiments in this direc­ tion aim at elucidating the folding code in the long run, but help to exploit the role of individual amino acid residues in catalysis, pro­ tein stability, and binding specificity in selected proteins now.

Reseña del editor

The main topic of this 39th Mosbacher Colloquium is concerned with techniques of protein engineering, examples of application, and the analysis and determination of protein structure, their stability and flexibility. Physicochemical aspects of hydrophobic interactions, folding dynamics, energy and entropy changes during conformational changes of peptide or protein chains, and the molecular events during catalytic processes, as well as ligand binding of a given enzyme are comprehensively treated. Furthermore, the implications for designing new biologically active peptides and synthetic antibodies are discussed.

Über diese Auflage

• Verlag: Springer
• Erscheinungsdatum: 2013
• ISBN 10: 3642741754
• ISBN 13: 9783642741753
• Einband: Tapa blanda
• Anzahl der Seiten: 148
• Herausgeber: Winnacker Ernst-Ludwig