The genome of retroviruses contains three major coding regions for virion proteins, gag, pol and env. Gag encompasses information for nonglycosylated viral proteins that form the matrix, the capsid and the nucleoprotein structures. From pol derive reverse transcriptase and integrase, and env codes for the surface glycoproteins of the virion which consist of a transmembrane and a surface domain, linked by disulfide bonds. A viral protease is derived eitherfrom the gagorfrom the pol coding region, depending on the virus. Simple retroviruses contain only this elementary gag, pol, and env coding information. Once integrated, they are able to multiply efficiently, using the cellular transcriptional and replication machineries without intervention of viral transacting factors. Most oncogenic retroviruses belong in this category. Complex retroviruses, on the other hand, encode additional nonstructural proteins from multiply spliced messages. These proteins play important regulatory roles in the life cycle of the virus. They function as transacting factors that, in concert with cellular regulatory proteins, control viral gene expression and function and are essential components in the replication of complex retroviruses. To this category belong the lentiviruses, the spumaviruses and a group of oncogenic retroviruses that includes human T cell leukemia virus (HTLV) and bovine leukosis virus(BLV).
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The genome of retroviruses contains three major coding regions for virion proteins, gag, pol and env. Gag encompasses information for nonglycosylated viral proteins that form the matrix, the capsid and the nucleoprotein structures. From pol derive reverse transcriptase and integrase, and env codes for the surface glycoproteins of the virion which consist of a transmembrane and a surface domain, linked by disulfide bonds. A viral protease is derived eitherfrom the gagorfrom the pol coding region, depending on the virus. Simple retroviruses contain only this elementary gag, pol, and env coding information. Once integrated, they are able to multiply efficiently, using the cellular transcriptional and replication machineries without intervention of viral transacting factors. Most oncogenic retroviruses belong in this category. Complex retroviruses, on the other hand, encode additional nonstructural proteins from multiply spliced messages. These proteins play important regulatory roles in the life cycle of the virus. They function as transacting factors that, in concert with cellular regulatory proteins, control viral gene expression and function and are essential components in the replication of complex retroviruses. To this category belong the lentiviruses, the spumaviruses and a group of oncogenic retroviruses that includes human T cell leukemia virus (HTLV) and bovine leukosis virus(BLV).
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The genome of retroviruses contains three major coding regions for virion proteins, gag, pol and env. Gag encompasses information for nonglycosylated viral proteins that form the matrix, the capsid and the nucleoprotein structures. From pol derive reverse transcriptase and integrase, and env codes for the surface glycoproteins of the virion which consist of a transmembrane and a surface domain, linked by disulfide bonds. A viral protease is derived eitherfrom the gagorfrom the pol coding region, depending on the virus. Simple retroviruses contain only this elementary gag, pol, and env coding information. Once integrated, they are able to multiply efficiently, using the cellular transcriptional and replication machineries without intervention of viral transacting factors. Most oncogenic retroviruses belong in this category. Complex retroviruses, on the other hand, encode additional nonstructural proteins from multiply spliced messages. These proteins play important regulatory roles in the life cycle of the virus. They function as transacting factors that, in concert with cellular regulatory proteins, control viral gene expression and function and are essential components in the replication of complex retroviruses. To this category belong the lentiviruses, the spumaviruses and a group of oncogenic retroviruses that includes human T cell leukemia virus (HTLV) and bovine leukosis virus(BLV). 256 pp. Englisch. Bestandsnummer des Verkäufers 9783642789311
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. List of Contents.- Regulation of Foamy Virus Gene Expression.- Transactivation of Cellular Genes by Human Retroviruses.- Regulation of Human Immunodeficiency Virus Type 1 Gene Expression by the Transactivator Protein Tat.- HTLV-1 Oncoprotein Tax and Cellula. Bestandsnummer des Verkäufers 5070700
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The genome of retroviruses contains three major coding regions for virion proteins, gag, pol and env. Gag encompasses information for nonglycosylated viral proteins that form the matrix, the capsid and the nucleoprotein structures. From pol derive reverse transcriptase and integrase, and env codes for the surface glycoproteins of the virion which consist of a transmembrane and a surface domain, linked by disulfide bonds. A viral protease is derived eitherfrom the gagorfrom the pol coding region, depending on the virus. Simple retroviruses contain only this elementary gag, pol, and env coding information. Once integrated, they are able to multiply efficiently, using the cellular transcriptional and replication machineries without intervention of viral transacting factors. Most oncogenic retroviruses belong in this category. Complex retroviruses, on the other hand, encode additional nonstructural proteins from multiply spliced messages. These proteins play important regulatory roles in the life cycle of the virus. They function as transacting factors that, in concert with cellular regulatory proteins, control viral gene expression and function and are essential components in the replication of complex retroviruses. To this category belong the lentiviruses, the spumaviruses and a group of oncogenic retroviruses that includes human T cell leukemia virus (HTLV) and bovine leukosis virus(BLV). Bestandsnummer des Verkäufers 9783642789311
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The genome of retroviruses contains three major coding regions for virion proteins, gag, pol and env. Gag encompasses information for nonglycosylated viral proteins that form the matrix, the capsid and the nucleoprotein structures. From pol derive reverse transcriptase and integrase, and env codes for the surface glycoproteins of the virion which consist of a transmembrane and a surface domain, linked by disulfide bonds. A viral protease is derived eitherfrom the gagorfrom the pol coding region, depending on the virus. Simple retroviruses contain only this elementary gag, pol, and env coding information. Once integrated, they are able to multiply efficiently, using the cellular transcriptional and replication machineries without intervention of viral transacting factors. Most oncogenic retroviruses belong in this category. Complex retroviruses, on the other hand, encode additional nonstructural proteins from multiply spliced messages. These proteins play important regulatory roles in the life cycle of the virus. They function as transacting factors that, in concert with cellular regulatory proteins, control viral gene expression and function and are essential components in the replication of complex retroviruses. To this category belong the lentiviruses, the spumaviruses and a group of oncogenic retroviruses that includes human T cell leukemia virus (HTLV) and bovine leukosis virus(BLV).Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch. Bestandsnummer des Verkäufers 9783642789311
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