Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation (BestMasters) - Softcover

Buch 26 von 91: BestMasters

Loos, Carolin

 
9783658132330: Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation (BestMasters)
Softcover
ISBN 10: 3658132337 ISBN 13: 9783658132330
Verlag: Springer Spektrum, 2016

Inhaltsangabe

Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information. 

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Über die Autorin bzw. den Autor

Carolin Loos is currently doing her PhD at the Institute of Computational Biology at the Helmholtz Zentrum München. She is member of the junior research group „Data-driven Computational Modeling“. 

Von der hinteren Coverseite

Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information.

Contents

  • Modeling and Parameter Estimation for Single-Cell Data
  • ODE Constrained Mixture Modeling for Multivariate Data
  • Approximate Bayesian Computation Using Multivariate Statistics

Target Groups

    Researchers and students in the fields of (bio-)mathematics, statistics, bioinformatics
  • System biologists, biostatisticians, bioinformaticians

The Author
Carolin Loos is currently doing her PhD at the Institute of Computational Biology at the Helmholtz Zentrum München. She is member of the junior research group Data-driven Computational Modeling .


„Über diesen Titel“ kann sich auf eine andere Ausgabe dieses Titels beziehen.

Verlag
Springer Spektrum
Erscheinungsdatum
2016
Sprache
Englisch
ISBN 10 
3658132337
ISBN 13 
9783658132330
Einband
Tapa blanda
Auflage
1
Anzahl der Seiten
116
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Nicht verfügbar

Weitere beliebte Ausgaben desselben Titels

9783658132354: Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation

Vorgestellte Ausgabe

ISBN 10:  3658132353 ISBN 13:  9783658132354
Verlag: Springer Spektrum, 2016
Softcover