Fluorescent dyes are of great importance for investigation of biological processes. In 2007 the first ratiometric fluorescent probe for apoptosis detection (F2N12S) has been reported. This book is focused on a development of the improved analogs of F2N12S. Firstly, the systematic studies of F2N12S in model membranes and cells are described for better understanding of its mechanism of response to apoptosis. Secondly, synthesis of new membrane probes is presented. All the molecules are classified into three types according to their sensitivity profiles (sensitive both to the surface charge and to the phase state, only to the surface charge and only to the phase state of lipid membranes). Nile Red derivative NR12S is introduced as a molecular sensor for apoptosis and cholesterol content in cell membrane. Also, the general principle for the design of fluorescent membrane probe is proposed. Finally, two new classes of environment-sensitive fluorophores are presented (on the base of fluorene and chromone units). This book should be interesting for those who are working in the field of biological membranes and on the development of new molecular tools for fluorescence imaging.
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Author was born in Kalush, one of regional centers in western Ukraine. After school studies he entered the Kyiv National University (2002), where he got the master degree in organic chemistry (2007). After that author arrived to France where he enjoyed picnics, swimming and making science at the University of Strasbourg.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fluorescent dyes are of great importance for investigation of biological processes. In 2007 the first ratiometric fluorescent probe for apoptosis detection (F2N12S) has been reported. This book is focused on a development of the improved analogs of F2N12S. Firstly, the systematic studies of F2N12S in model membranes and cells are described for better understanding of its mechanism of response to apoptosis. Secondly, synthesis of new membrane probes is presented. All the molecules are classified into three types according to their sensitivity profiles (sensitive both to the surface charge and to the phase state, only to the surface charge and only to the phase state of lipid membranes). Nile Red derivative NR12S is introduced as a molecular sensor for apoptosis and cholesterol content in cell membrane. Also, the general principle for the design of fluorescent membrane probe is proposed. Finally, two new classes of environment-sensitive fluorophores are presented (on the base of fluorene and chromone units). This book should be interesting for those who are working in the field of biological membranes and on the development of new molecular tools for fluorescence imaging. 156 pp. Englisch. Bestandsnummer des Verkäufers 9783659181009
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kucherak OleksandrAuthor was born in Kalush, one of regional centers in western Ukraine. After school studies he entered the Kyiv National University (2002), where he got the master degree in organic chemistry (2007). After that auth. Bestandsnummer des Verkäufers 5137538
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Fluorescent dyes are of great importance for investigation of biological processes. In 2007 the first ratiometric fluorescent probe for apoptosis detection (F2N12S) has been reported. This book is focused on a development of the improved analogs of F2N12S. Firstly, the systematic studies of F2N12S in model membranes and cells are described for better understanding of its mechanism of response to apoptosis. Secondly, synthesis of new membrane probes is presented. All the molecules are classified into three types according to their sensitivity profiles (sensitive both to the surface charge and to the phase state, only to the surface charge and only to the phase state of lipid membranes). Nile Red derivative NR12S is introduced as a molecular sensor for apoptosis and cholesterol content in cell membrane. Also, the general principle for the design of fluorescent membrane probe is proposed. Finally, two new classes of environment-sensitive fluorophores are presented (on the base of fluorene and chromone units). This book should be interesting for those who are working in the field of biological membranes and on the development of new molecular tools for fluorescence imaging.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 156 pp. Englisch. Bestandsnummer des Verkäufers 9783659181009
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Fluorescent dyes are of great importance for investigation of biological processes. In 2007 the first ratiometric fluorescent probe for apoptosis detection (F2N12S) has been reported. This book is focused on a development of the improved analogs of F2N12S. Firstly, the systematic studies of F2N12S in model membranes and cells are described for better understanding of its mechanism of response to apoptosis. Secondly, synthesis of new membrane probes is presented. All the molecules are classified into three types according to their sensitivity profiles (sensitive both to the surface charge and to the phase state, only to the surface charge and only to the phase state of lipid membranes). Nile Red derivative NR12S is introduced as a molecular sensor for apoptosis and cholesterol content in cell membrane. Also, the general principle for the design of fluorescent membrane probe is proposed. Finally, two new classes of environment-sensitive fluorophores are presented (on the base of fluorene and chromone units). This book should be interesting for those who are working in the field of biological membranes and on the development of new molecular tools for fluorescence imaging. Bestandsnummer des Verkäufers 9783659181009
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Taschenbuch. Zustand: Neu. Fluorescent Membrane Probes for Apoptosis and Raft Domains | Design, Synthesis and Application | Oleksandr Kucherak | Taschenbuch | 156 S. | Englisch | 2012 | LAP LAMBERT Academic Publishing | EAN 9783659181009 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 106342076
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