Development of solid self nano emulsified tablet of furosemide: Formulation & Optimization of Solid Selfeulsified Tablet of BCS IV drug furosemide to enhance bioavailability - Softcover

Prajapati, Bhupendra; Patel, Hitesh K.

 
9783659247811: Development of solid self nano emulsified tablet of furosemide: Formulation & Optimization of Solid Selfeulsified Tablet of BCS IV drug furosemide to enhance bioavailability
Softcover
ISBN 10: 3659247812 ISBN 13: 9783659247811
Verlag: LAP LAMBERT Academic Publishing, 2012

Inhaltsangabe

Interest in Lipid Based Drug Delivery (LBDD) is relatively recent and relates to the developments in the past 10 to 15 years, largely driven by the growing need for novel drug delivery systems to deal with the vast majority of the new chemical entities (NCE) that have poor solubility or permeability, to improve the delivery of existing drugs, and for line extensions. Other applications include drug coating for either taste masking or protection of the active, and in sustained release dosage forms. Successful drug design with lipids depends largely on understanding the physical–chemical and physiological factors that promote or inhibit bioavailability. It requires a grasp of not only the drug candidate issues but also the role of the drug delivery system or the potential for drug-excipient interplay in vitro as well as in vivo conditions. Depending on the choice of excipient(s) and formulation techniques, it is possible to obtain a variety of systems including physical mixtures, liquid/solid solutions, solid dispersions, and Self-Micro or Self-Nano Emulsifying Drug Delivery Systems (SMEDDS/SNEDDS). These systems may then be incorporated into tablets by absorbing on to absorbents.

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Über die Autorin bzw. den Autor

Dr. B.G.Prajapati (PhD and M.Pharm in Pharmaceutics and Pharmaceutical Technology), working as a Associate Professor since Four years at S.K.Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, North Gujarat, India. He has 10 years of experience in academic/industry.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
3659247812
ISBN 13 
9783659247811
Einband
Taschenbuch
Anzahl der Seiten
152
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Fastbook Publishing
customerservice@vdm-vsg.de

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Riga
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