Engineering Genetic Logic Gates: Design and Functional Assembly of Synthetic Biological Circuits - Softcover

Wang, Baojun

 
9783659274794: Engineering Genetic Logic Gates: Design and Functional Assembly of Synthetic Biological Circuits
Softcover
ISBN 10: 3659274798 ISBN 13: 9783659274794
Verlag: LAP LAMBERT Academic Publishing, 2012

Inhaltsangabe

Programming living cells with synthetic gene circuits to perform desired tasks has been a major theme in the growing field of synthetic biology. However, gene circuit engineering currently lacks the same predictability and reliability as seen in other mature engineering disciplines. This book introduces the design methodology for engineering novel modular and orthogonal genetic logic devices, and the predictable functional assembly of modular biological components into customisable biological circuits. Various genetic logic devices, including AND, NOT and NAND gates, were constructed in Escherichia coli bacteria to achieve customised cellular computing and sensing. An effective parts-based engineering approach is presented for assembling individual biological parts into functional circuits using engineered ‘in-context’ characterised modules aided by modelling. The book is a pioneering work in the field, and should be useful for engineers who would like to engineer synthetic biological systems for human desired purposes and for biologists who are interested in the design principles of natural biological circuits.

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Über die Autorin bzw. den Autor

Dr Baojun Wang obtained his PhD degree in Bioengineering at Imperial College London. His research centres on the design and engineering of synthetic biological devices and circuits for customised cellular computing and sensing. He is currently a Research Fellow at Imperial and works on building an interface between cellular and electronic systems.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
3659274798
ISBN 13 
9783659274794
Einband
Taschenbuch
Anzahl der Seiten
208
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Editions Muse
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