Thiourea Derivatives As Antimicrobials: Synthesis, Biological Activity And Potentiation By Nanotechnological Solutions - Softcover

Limban, Carmen; Chifiriuc, Mariana Carmen; Grumezescu, Alexandru Mihai

Softcover

ISBN 10: 3659385409 ISBN 13: 9783659385407

Verlag: LAP LAMBERT Academic Publishing, 2013

Über diesen Titel

Reseña del editor:

Infectious diseases remain as a major world health problem due to the rapid development of resistance to the existing antimicrobial drugs. The spread of resistance among Gram-positive and Gram-negative bacteria as well as fungal pathogens, correlated with increasing limitation in the availability of therapeutic options represent a growing challenge for the development of new antimicrobials. The purpose of this book is to present an updated perspective upon the use of thiourea derivatives as antimicrobial agents, as well as the combination with nanoparticles for enhancing their antimicrobial efficacy, in order to highlight potential new solutions to cope with infections resulting from drug-resistant and biofilm forming microorganisms. The thiourea derivatives could represent novel and promising antimicrobials, which target not only the actively growing microorganisms, but also the non-multiplying, biofilm embedded microbial cells. Moreover, using novel core/shell/adsorption-shell to inhibit the microbial adherence could be of a great interest for the biomedical field, opening new directions for the design of film-coated surfaces with improved anti-biofilm properties.

Biografía del autor:

Dr. Carmen Limban has an extensive experience in the synthesis, structural, physico-chemical characterization and bioevaluation of new classes of organic chemical compounds with pharmacological activity, being the author of numerous research projects, books, patents and papers in this field.

Über diese Auflage

• Verlag: LAP LAMBERT Academic Publishing
• Erscheinungsdatum: 2013
• ISBN 10: 3659385409
• ISBN 13: 9783659385407
• Einband: Tapa blanda
• Anzahl der Seiten: 88