Development of Self Microemulsifying Drug Delivery System: Design and Development of Self Microemulsifying Drug Delivery System of Clopidogrel Bisulphate - Softcover

Patel, Priyank B.; Patel, Mukesh R.

 
9783659404795: Development of Self Microemulsifying Drug Delivery System: Design and Development of Self Microemulsifying Drug Delivery System of Clopidogrel Bisulphate
Softcover
ISBN 10: 3659404799 ISBN 13: 9783659404795
Verlag: LAP LAMBERT Academic Publishing, 2013

Inhaltsangabe

Nearly 40% of new drug candidates exhibit low solubility in water, which leads to poor oral bioavailability, high intra- and inter-subject variability and lack of dose proportionality. Modification of the physicochemical properties, such as salt formation and particle size reduction of the compound may be one approach to improve the dissolution rate. . In recent years, much attention has focused on lipid based formulations to improve the oral bioavailability of poorly water soluble drug compounds. In fact, the most popular approach is the incorporation of the drug compound into inert lipid vehicles such as oils, surfactant dispersions, self-emulsifying formulations, emulsions and liposomes with particular emphasis on self microemulsifying drug delivery systems (SMEDDS).

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Reseña del editor

Nearly 40% of new drug candidates exhibit low solubility in water, which leads to poor oral bioavailability, high intra- and inter-subject variability and lack of dose proportionality. Modification of the physicochemical properties, such as salt formation and particle size reduction of the compound may be one approach to improve the dissolution rate. . In recent years, much attention has focused on lipid based formulations to improve the oral bioavailability of poorly water soluble drug compounds. In fact, the most popular approach is the incorporation of the drug compound into inert lipid vehicles such as oils, surfactant dispersions, self-emulsifying formulations, emulsions and liposomes with particular emphasis on self microemulsifying drug delivery systems (SMEDDS).

Biografía del autor

Priyank B. Patel(P.G.student), Dr. Mukesh R. Patel(head of Department of Pharmaceutics),Shri B.M.Shah College of Pharmaceutical Education and Research, Modasa-383315, India

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2013
Sprache
Englisch
ISBN 10 
3659404799
ISBN 13 
9783659404795
Einband
Tapa blanda
Anzahl der Seiten
108
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Nicht verfügbar

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Vorgestellte Ausgabe

ISBN 10:  3844331824 ISBN 13:  9783844331820
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Softcover