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Design And Development of Alfuzosin HCL Floating Microspheres: Floating Microspheres of Alfuzosin HCl - Softcover

Shah, Megha; Patel, Mukesh R.

 
9783659427886: Design And Development of Alfuzosin HCL Floating Microspheres: Floating Microspheres of Alfuzosin HCl
Softcover
ISBN 10: 3659427888 ISBN 13: 9783659427886
Verlag: LAP LAMBERT Academic Publishing, 2013

Inhaltsangabe

The purpose was to formulate Floating microspheres of Alfuzosin HCl, an orally administered alpha adrenergic blocker used to treat benign prostatic hyperplasia with a view of improving its oral bioavailability and giving a prolonged release of drug.Floating microspheres with biocompatible enteric acrylic polymer such as Eudragit S100 and cellulose polymers such as HPMC K100 M were successfully prepared by emulsion solvent evaporation method. The particle size analysis revealed that the size of microspheres was found to increase with increase in the concentration of polymer.. In vitro drug release studies showed that the release of drug decreases with increases drug to polymer ration of microspheres. . From the stability study it was found that there was no significant change in the physical appearance, drug entrapment, release characteristics and floating behavior of the microspheres.

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Über die Autorin bzw. den Autor

Shah Megha.A,M.pharm in Pharmaceutics, Shri B.M.ShahCollege of Pharmaceutical Education and Research,Modasa-383315,Gujarat,India.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2013
Sprache
Englisch
ISBN 10 
3659427888
ISBN 13 
9783659427886
Einband
Taschenbuch
Anzahl der Seiten
184
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
JustFiction Edition
customerservice@vdm-vsg.de

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Riga
1039
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