Factorial design as optimization technique was applied in formulation development and processing conditions of Diclofenac sodium granules. The present study involves design and evaluation of non-effervescent granules of Diclofenac sodium with excellent flow properties. In the formulation of non-effervescent granules of Diclofenac sodium, angle of repose was the dependent variable (with excellent flow) and the concentrations of binder (Povidone K-30) and lubricant (Magnesium stearate) were the two independent variables chosen at two different levels. With the help of factorial approach, a polynomial equation Y= B0 + B1X1 + B2X2 + B12X1X2 was formed. Using the polynomial equation three new formulations were selected and performed to evaluate the correlation between experimental and predicted responses. A good correlation was obtained between the experimental and the predicted values. Also the work was oriented to have a comparative study of application of factorial design with and without use of software and come up with any pros and cons of these respective ways.
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Dr. Mrs. Pradnya Palekar - Shanbhag is Professor in Pharmaceutics and Principal of Saraswathi Vidya Bhavans College of Pharmacy affiliated to University of Mumbai. She completed M. Pharm. and Ph.D. (Tech.) from Institute of Chemical Technology. She is a life member of Association of Pharmaceutical teachers, a reviewer for scientific journals.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Factorial design as optimization technique was applied in formulation development and processing conditions of Diclofenac sodium granules. The present study involves design and evaluation of non-effervescent granules of Diclofenac sodium with excellent flow properties. In the formulation of non-effervescent granules of Diclofenac sodium, angle of repose was the dependent variable (with excellent flow) and the concentrations of binder (Povidone K-30) and lubricant (Magnesium stearate) were the two independent variables chosen at two different levels. With the help of factorial approach, a polynomial equation Y= B0 + B1X1 + B2X2 + B12X1X2 was formed. Using the polynomial equation three new formulations were selected and performed to evaluate the correlation between experimental and predicted responses. A good correlation was obtained between the experimental and the predicted values. Also the work was oriented to have a comparative study of application of factorial design with and without use of software and come up with any pros and cons of these respective ways. 76 pp. Englisch. Bestandsnummer des Verkäufers 9783659460111
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Factorial design as optimization technique was applied in formulation development and processing conditions of Diclofenac sodium granules. The present study involves design and evaluation of non-effervescent granules of Diclofenac sodium with excellent flow properties. In the formulation of non-effervescent granules of Diclofenac sodium, angle of repose was the dependent variable (with excellent flow) and the concentrations of binder (Povidone K-30) and lubricant (Magnesium stearate) were the two independent variables chosen at two different levels. With the help of factorial approach, a polynomial equation Y= B0 + B1X1 + B2X2 + B12X1X2 was formed. Using the polynomial equation three new formulations were selected and performed to evaluate the correlation between experimental and predicted responses. A good correlation was obtained between the experimental and the predicted values. Also the work was oriented to have a comparative study of application of factorial design with and without use of software and come up with any pros and cons of these respective ways.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 76 pp. Englisch. Bestandsnummer des Verkäufers 9783659460111
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Factorial design as optimization technique was applied in formulation development and processing conditions of Diclofenac sodium granules. The present study involves design and evaluation of non-effervescent granules of Diclofenac sodium with excellent flow properties. In the formulation of non-effervescent granules of Diclofenac sodium, angle of repose was the dependent variable (with excellent flow) and the concentrations of binder (Povidone K-30) and lubricant (Magnesium stearate) were the two independent variables chosen at two different levels. With the help of factorial approach, a polynomial equation Y= B0 + B1X1 + B2X2 + B12X1X2 was formed. Using the polynomial equation three new formulations were selected and performed to evaluate the correlation between experimental and predicted responses. A good correlation was obtained between the experimental and the predicted values. Also the work was oriented to have a comparative study of application of factorial design with and without use of software and come up with any pros and cons of these respective ways. Bestandsnummer des Verkäufers 9783659460111
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Taschenbuch. Zustand: Neu. Factorial Design: A Comparative Study With And Without Use of Software | A Comparative Factorial Design Approach In Pharmaceutical Formulations | Pradnya Palekar - Shanbhag (u. a.) | Taschenbuch | 76 S. | Englisch | 2015 | LAP LAMBERT Academic Publishing | EAN 9783659460111 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 104762304
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