Proteomic Analysis of Kir6.2 Using Bioinformatics Software Tools - Softcover

Sugapriya Menaga, Paulraj

 
9783659513855: Proteomic Analysis of Kir6.2 Using Bioinformatics Software Tools
Softcover
ISBN 10: 3659513857 ISBN 13: 9783659513855
Verlag: LAP LAMBERT Academic Publishing, 2014

Inhaltsangabe

KATP Channels couple glucose metabolism to membrane potential and thus play a central role in glucose stimulated insulin secretion. Genetic mutations in the genes encoding the channel subunits (Kir 6.2) can cause Congenital Hyperinsulinism (CHI). BLAST and FASTA similarity searches reveals the closely relatedness of Kir6.2 with other inwardly rectifying K+ channel family of proteins. The phylogenetic analysis showed the evolutionary relationship of various mammals with reference to Kir6.2. The secondary structure prediction, Tranmembrane and hydropathy prediction reveals the Kir6.2 contained more number of helical regions.Further, the Kir6.2 protein contains motifs which are responsible for Prokaryotic membrane lipoprotein lipid attachment site, cAMP and cGMP dependent protein kinase, casein kinase II and Protein Kinase C phosphorylation site.

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Über die Autorin bzw. den Autor

Sugapriyamenaga Paulraj is having 9 years of teaching experience and currently working as Assistant Professor in Biotechnology, ANJAC, Sivakasi. She completed UG Biochemistry, PG Integrated Biology, ADBI, PGDCA & MPhil in Biotech.Received two TNSCST Projects & guided 20 M.Sc. student Projects. The Author is having good knowledge in Bioinformatics.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2014
Sprache
Englisch
ISBN 10 
3659513857
ISBN 13 
9783659513855
Einband
Taschenbuch
Anzahl der Seiten
104
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Edicoes Nosso Conhecimento
customerservice@vdm-vsg.de

SIA
Riga
1039
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