Verwandte Artikel zu Benzothiazole – A Biologically Important Scaffold

Benzothiazole – A Biologically Important Scaffold - Softcover

P. Prabhu, Padmavathi; Shastry, C. S.; Panneer Selvam, Theivendren

 
9783659523328: Benzothiazole – A Biologically Important Scaffold
Softcover
ISBN 10: 3659523321 ISBN 13: 9783659523328
Verlag: LAP LAMBERT Academic Publishing, 2014

Inhaltsangabe

Development in biological evaluation of heterocyclic molecules has undergone manifold changes and the advancement in molecular biology has eased the design of new molecules based on their mechanism of action. Proposed work is based upon the development of newer analogues of benzothiazoles followed by their biological evaluation. Benzothiazoles have been reported with good biological activities ranging from antiparasitic, anti-inflammatory, antitumour, p56lck inhibition, immunosuppressive antitubercular activity etc. The derivatives of benzothiazoles have been developed very recently, targeting antitumour activity by various workers. The type of molecules are reported to act based upon their interaction with aryl hydrocarbon receptor as well as their interaction with p56lck. Reports are available mentioning the importance of metabolism and the deactivation of the molecules with respect to their biopotency.This gives an additional avenue for the researchers to work upon the concept of prodrug and mutual prodrugs of these bioactive molecules and come up with better activity profile. With this background, we thought to develop newer analogues of the nucleus benzothiazole.

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Über die Autorin bzw. den Autor

Mrs. Padmavathi P Prabhu M.Pharm (Ph.D)Assistant ProfessorSrinivas College of Pharmacy, Mangalore, D.K. district, Karnataka, INDIADr. C.S.Shastry, M.Pharm., Ph.D.,ProfessorNGSMIPS, Mangalore, D.K. district, Karnataka, INDIADr. T. PanneerSelvam M.Pharm., Ph.D Assistant ProfessorPES's R&TB College of Pharmacy, Farmagudi, Ponda, Goa, INDIA

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2014
Sprache
Englisch
ISBN 10 
3659523321
ISBN 13 
9783659523328
Einband
Taschenbuch
Anzahl der Seiten
192
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
info@bod.de
info@bod.de

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